BXPC3 Cell Line human

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 93120816, human pancreas, Epithelial

• Synonym(s): Biopsy Xenograft of Pancreatic Carcinoma Cell Line-3, BxPC-3 Cells
• UNSPSC Code: 41106514

Properties

• biological source: human pancreas
• description: Human primary pancreatic adenocarcinoma
• packaging: tube of 5 μg 93120816-DNA-5UG; pkg of vial of cells 93120816-1VL
• growth mode: Adherent
• karyotype: 2n = 59, near triploid
• morphology: Epithelial
• products: Mucin
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cancer
• shipped in: dry ice
• storage temp.: −196°C

Description

Application

BXPC3 cell line has been used to determine the biological and therapeutic importance of gastrin gene expression in pancreatic adenocarcinomas.

Tumourigenicity studies

Biochem/physiol Actions

Derived from a 61 year old female with a primary adenocarcinoma of the pancreas. BxPC-3 cells produce mucin and the tumour produced in a nude mouse is moderately well to poorly differentiated like the primary adenocarcinoma.

Human primary pancreatic adenocarcinoma

STR-PCR Data: Amelogenin: X
CSF1PO: 13
D13S317: 11
D16S539: 9,11
D5S818: 11
D7S820: 10,13
THO1: 9
TPOX: 8
vWA: 14,18

Preparation Note

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4x10,000 cells/cm² using 0.25% trypsin/EDTA; 5% CO₂; 37°C.

Other Notes

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