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D1156

Sigma-Aldrich

N,N-Dimethylglycine

≥99%

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Synonym(s):
(Dimethylamino)acetic acid
Linear Formula:
(CH3)2NCH2COOH
CAS Number:
Molecular Weight:
103.12
Beilstein/REAXYS Number:
1700261
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥99%

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

178-182 °C (lit.)

application(s)

peptide synthesis

SMILES string

CN(C)CC(O)=O

InChI

1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)

InChI key

FFDGPVCHZBVARC-UHFFFAOYSA-N

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1 of 4

This Item
D6382A1879H7750
N,N-Dimethylglycine ≥99%

D1156

N,N-Dimethylglycine

N,N-Dimethylglycine hydrochloride

D6382

N,N-Dimethylglycine hydrochloride

L-2-Aminobutyric acid ≥99% (titration)

A1879

L-2-Aminobutyric acid

DL-Histidine ≥99% (TLC)

H7750

DL-Histidine

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

technique(s)

ligand binding assay: suitable

assay

≥99%

assay

≥98%

assay

≥99% (titration)

assay

≥99% (TLC)

mp

178-182 °C (lit.)

mp

189-194 °C (lit.)

mp

-

mp

273 °C (dec.) (lit.)

color

white to off-white

color

white

color

white

color

-

application(s)

peptide synthesis

application(s)

-

application(s)

peptide synthesis

application(s)

peptide synthesis

Biochem/physiol Actions

N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Customers Also Viewed

Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
S H Moolenaar et al.
Clinical chemistry, 45(4), 459-464 (1999-04-02)
A38-year-old man presented with a history of fish odor (since age 5) and unusual muscle fatigue with increased serum creatine kinase. Our aim was to identify the metabolic error in this new condition. We used 1H NMR spectroscopy to study
B A Binzak et al.
American journal of human genetics, 68(4), 839-847 (2001-03-07)
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and
Isabelle D Kalmar et al.
The British journal of nutrition, 107(11), 1635-1644 (2011-09-21)
N,N-Dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. The objective of the present trial was to evaluate tolerance, safety and bioaccumulation of dietary DMG in broilers when supplemented at 1 g
D Vanhauteghem et al.
Amino acids, 43(1), 245-253 (2011-09-14)
The current study first investigates the emulsifying potential of glycine and its N-methylated derivatives N-methylglycine (sarcosine), N,N-dimethylglycine (DMG) and N,N,N-trimethylglycine (betaine) under varying pH conditions. Subsequently, the effect of these test compounds on the membrane integrity of enterotoxigenic Escherichia coli

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