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S7672

Sigma-Aldrich

Sarcosine

≥98%, suitable for HPLC, BioXtra

Synonym(s):

N-Methylglycine

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About This Item

Linear Formula:
CH3NHCH2COOH
CAS Number:
Molecular Weight:
89.09
Beilstein/REAXYS Number:
1699442
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26

product name

Sarcosine, BioXtra

product line

BioXtra

Quality Level

assay

≥98%

form

powder

technique(s)

HPLC: suitable

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white

mp

208-212 °C (dec.) (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.5%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.1%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

cell analysis

SMILES string

CNCC(O)=O

InChI

1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)

InChI key

FSYKKLYZXJSNPZ-UHFFFAOYSA-N

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Application


  • Glyphosate resistance and biodegradation by Burkholderia cenocepacia CEIB S5-2.: This study explores the role of sarcosine in glyphosate resistance and biodegradation by Burkholderia cenocepacia CEIB S5-2, highlighting its potential in environmental biotechnology (Díaz-Soto et al., 2024).

  • CYP116B5-SOX: An artificial peroxygenase for drug metabolites production and bioremediation.: Sarcosine is utilized in developing a novel artificial peroxygenase, enhancing bioremediation and drug metabolite production applications (Giuriato et al., 2024).

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zhiyi Wu et al.
The Journal of physiology, 598(16), 3417-3438 (2020-05-24)
Loss-of-function mutations in proteins found at glycinergic synapses, most commonly in the α1 subunit of the glycine receptor (GlyR), cause the startle disease/hyperekplexia channelopathy in man. It was recently proposed that the receptors responsible are presynaptic homomeric GlyRs, rather than
Florian Jentzmik et al.
The Journal of urology, 185(2), 706-711 (2010-12-21)
Sarcosine in prostate cancer tissue samples was recently reported to be increased during prostate cancer progression to metastasis and suggested to be a key metabolite of cancer cell invasion and aggressiveness. We reevaluated sarcosine in prostate cancer tissue samples as
D S Lim et al.
Journal of the American College of Cardiology, 38(4), 1175-1180 (2001-10-05)
The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and
Eri Hara et al.
Biochimica et biophysica acta, 1830(8), 4046-4052 (2013-04-03)
Nanoparticle of Lactosome, which is composed of poly(l-lactic acid)-base depsipeptide with diameter of 35nm, accumulates in solid tumors by the enhanced permeability and retention (EPR) effect. However, a pharmacokinetic alteration of Lactosome was observed when Lactosome was repeatedly administered. This
Apolline Imbard et al.
Clinical chemistry and laboratory medicine, 51(3), 683-692 (2012-10-26)
Choline is essential for mammalian cell function. It plays a critical role in cell membrane integrity, neurotransmission, cell signaling and lipid metabolism. Moreover, choline is involved in methylation in two ways: a) its synthesis requires methyl groups donated by S-adenosyl-methionine

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