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D8517

Sigma-Aldrich

Iron–Dextran

95-105 mg/mL (Iron content), solution

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Synonym(s):
Ferric hydroxide dextran complex
CAS Number:
MDL number:
NACRES:
NA.25

biological source

synthetic

Quality Level

sterility

aseptically filled

Assay

95-105 mg/mL (Iron content)

form

solution

contains

0.5% phenol as preservative

composition

Iron, ~100 mg/mL

color

brown

useful pH range

4 - 6.5

storage temp.

room temp

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

InChI key

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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1 of 4

This Item
737669000890475
Sigma-Aldrich

Sigma-Aldrich

D8517

Iron–Dextran

Sigma-Aldrich

Sigma-Aldrich

90008

Blue Dextran

Sigma-Aldrich

Sigma-Aldrich

90475

Blue Dextran

form

solution

form

powder

form

powder

form

powder

color

brown

color

-

color

-

color

-

useful pH range

4 - 6.5

useful pH range

-

useful pH range

-

useful pH range

-

storage temp.

room temp

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

Application

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 1B - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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25G
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705578-5MG-PW

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MMYOMAG-74K-13

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Dextran 70

Raymond J Bergeron et al.
Journal of medicinal chemistry, 51(13), 3913-3923 (2008-06-07)
A series of iron-clearing efficiencies (ICEs), ferrokinetics, and toxicity studies for ( S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid (deferitrin, 1), ( S)-4,5-dihydro-2-[2-hydroxy-4-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 2), and (S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylic acid ( 3) are reported. The ICEs in rodents are shown to be dose-dependent and saturable for
Yonggang Gao et al.
Journal of ethnopharmacology, 145(1), 254-260 (2012-11-14)
Danshen (Salvia miltiorrhiza) has been widely prescribed in traditional folk medicine for treatment of hepatic and cardiovascular diseases in China and other Asian countries for several hundred years. Sixty male mice were randomly divided into five groups: control, iron overload
Natacha E Piloni et al.
Toxicology, 314(1), 174-182 (2013-10-15)
An in vivo model in rat was developed by intraperitoneally administration of Fe-dextran to study oxidative stress triggered by Fe-overload in rat brain. Total Fe levels, as well as the labile iron pool (LIP) concentration, in brain from rats subjected
Yong Won Cho et al.
Sleep medicine, 14(3), 274-277 (2013-01-22)
Various techniques used to assess brain iron concentrations have demonstrated the presence of low iron stores in patients with restless legs syndrome (RLS). Previous open-label and randomized studies generally support the value of iron treatment for RLS symptoms. Only one
John C Wood et al.
Magnetic resonance in medicine, 60(1), 82-89 (2008-06-27)
MRI is gaining increasing importance for the noninvasive quantification of organ iron burden. Since transverse relaxation rates depend on iron distribution as well as iron concentration, physiologic and pharmacologic processes that alter iron distribution could change MRI calibration curves. This

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