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F9636

Sigma-Aldrich

IgG−FITC from human serum

~20 mg/mL, buffered aqueous solution

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Synonym(s):
IgG-Fluorescein isothiocyanate from human serum
MDL number:
NACRES:
NA.46

conjugate

FITC conjugate

form

buffered aqueous solution

concentration

~20 mg/mL

storage temp.

2-8°C

target post-translational modification

unmodified

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F0132F3512F5512
form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

concentration

~20 mg/mL

concentration

-

concentration

-

concentration

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

target post-translational modification

unmodified

target post-translational modification

unmodified

target post-translational modification

unmodified

target post-translational modification

unmodified

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

IgGs are glycoprotein antibodies that regulate immunological defense mechanisms such as phagocytosis and inflammatory responses . IgG also modulates complement-mediated cell lysis . IgG-FITC from human serum does not react with purified human IgA, IgG, IgM, and Bence Jones κ and lambda myeloma proteins. Additionally, the product does not react with serum from rat, goat, rabbit, guinea pig, and mouse.

Application

IgG-FITC from human serum is suitable for use in immunoaffinity purifications , and metal-enhanced fluorescence . The product may also be used for immunoelectrophoretic applications.

Linkage

Do not confuse with Anti-Human IgG–FITC conjugate.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Purification of immunoglobulins from Serum Using Thiophilic Cellulose Beads
Subramanian, A.
International Journal of Biochromatography, 5(I), 31-47 (2000)
C I Bindon et al.
The Journal of experimental medicine, 168(1), 127-142 (1988-07-01)
Humanized antibodies are likely to have a major role in therapy and it is important to define their interaction with physiological effectors. By comparing a matched series of chimeric human mAbs we found that igG1 was most efficient in complement
Vishakha Sabharwal et al.
Infection and immunity, 77(3), 1121-1127 (2009-01-14)
Strategies to limit complement deposition on Streptococcus pneumoniae are established as virulence features for invasive disease, but their role in respiratory tract infection requires further analysis. We evaluated complement C3 protein deposition on discordant S. pneumoniae isolates of the same
Tatsuro Endo et al.
Biotechnology journal, 11(6), 831-837 (2016-05-07)
The development of high-sensitive, and cost-effective novel biosensors have been strongly desired for future medical diagnostics. To develop novel biosensor, the authors focused on the specific optical characteristics of photonic crystal. In this study, a label-free optical biosensor, polymer-based two-dimensional
Selective nanopatterning of protein via ion-induced focusing and its application to metal-enhanced fluorescence.
Chang Gyu Woo et al.
Small (Weinheim an der Bergstrasse, Germany), 7(13), 1790-1794 (2011-05-14)

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