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G2901

Sigma-Aldrich

Gly-Pro p-nitroanilide p-toluenesulfonate salt

chromogenic, ~99% (TLC), powder

Synonym(s):

GPDA, Gly-Pro-pNA TosOH

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O4 · C7H8O3S
CAS Number:
65096-46-0
Molecular Weight:
464.49
MDL number:
MFCD00039007
UNSPSC Code:
12352204
PubChem Substance ID:
329799907
NACRES:
NA.32

product name

Gly-Pro p-nitroanilide p-toluenesulfonate salt, ~99% (TLC)

assay

~99% (TLC)

form

powder

solubility

1 M HCl: 50 mg/mL

storage temp.

−20°C

SMILES string

Cc1ccc(cc1)S(O)(=O)=O.NCC(=O)N2CCC[C@H]2C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C13H16N4O4.C7H8O3S/c14-8-12(18)16-7-1-2-11(16)13(19)15-9-3-5-10(6-4-9)17(20)21;1-6-2-4-7(5-3-6)11(8,9)10/h3-6,11H,1-2,7-8,14H2,(H,15,19);2-5H,1H3,(H,8,9,10)/t11-;/m0./s1

InChI key

XHLUWCXVWCBOPP-MERQFXBCSA-N

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Application

Gly-Pro p-nitroanilide p-toluenesulfonate salt has been used as a substrate to assay dipeptidyl peptidase IV (DPPIV) activity in serum, and brush border homogenates.

Substrates

Substrate for Dipeptidyl Peptidase IV.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Delphine Ley et al.
Scientific reports, 9(1), 18111-18111 (2019-12-04)
The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified. Nevertheless, long-term consequences of early environment on susceptibility to intestinal diseases have not
Ivana Z Matić et al.
Leukemia & lymphoma, 54(12), 2701-2706 (2013-03-09)
The aim of this research was to determine the serum dipeptidyl peptidase IV (DPPIV) activity as well as the percentages of CD26 + lymphocytes and CD26 + overall white blood cells in patients with hematological malignancies: non-Hodgkin lymphoma (NHL), Hodgkin
Ivana Z Matić et al.
BMC immunology, 13, 48-48 (2012-08-23)
Dipeptidyl peptidase IV, a multifunctional serine protease, is implicated in regulation of malignant transformation, promotion and further progression of cancer, exerting tumor-suppressing or even completely opposite - tumor-promoting activities. The aim of present research was to determine the serum DPPIV
Delphine Ley et al.
Scientific reports, 9(1), 18111-18111 (2019-12-04)
The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified. Nevertheless, long-term consequences of early environment on susceptibility to intestinal diseases have not
Anna Iwaniak et al.
International journal of molecular sciences, 22(6) (2021-04-04)
In silico and in vitro methods were used to analyze ACE- and DPP-IV-inhibiting potential of Gouda cheese with a modified content of β-casein. Firstly, the BIOPEP-UWM database was used to predict the presence of ACE and DPP-IV inhibitors in casein

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