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G3127

Sigma-Aldrich

Gly-Sar

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Synonym(s):
Glycyl-sarcosine
Linear Formula:
NH2CH2CON(CH3)CH2COOH
CAS Number:
Molecular Weight:
146.14
Beilstein/REAXYS Number:
1768450
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

assay

≥98% (TLC)

Quality Level

form

powder

color

white

mp

198 °C

storage temp.

−20°C

SMILES string

CN(CC(O)=O)C(=O)CN

InChI

1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)

InChI key

VYAMLSCELQQRAE-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Show Differences

1 of 4

This Item
G3502G3882G5386
Gly-Sar

G3127

Gly-Sar

Gly-Tyr

G3502

Gly-Tyr

Gly-Gly-Gly-Gly

G3882

Gly-Gly-Gly-Gly

Gly-Gly-Tyr-Arg ≥97% (HPLC)

G5386

Gly-Gly-Tyr-Arg

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥97% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mp

198 °C

mp

282 °C

mp

300 °C

mp

-

color

white

color

white

color

white to off-white

color

-

Gene Information

human ... SLC15A1(6564)

Gene Information

-

Gene Information

-

Gene Information

-

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Jinling Wang et al.
International journal of nanomedicine, 13, 7997-8012 (2018-12-13)
Polymeric micelles (PMs) hold promise for improving solubility and oral absorption of poorly soluble drugs. Unfortunately, the oral absorption of PMs is also limited by intestinal epithelium. To improve the oral delivery efficiency of micelles, transporter-mediated micelles could enhance the
Hovhannes J Gukasyan et al.
Pharmaceutical research, 34(12), 2488-2497 (2017-08-24)
Studies were conducted in primary cultured rat alveolar epithelial cell monolayers to characterize peptide transporter expression and function. Freshly isolated rat lung alveolar epithelial cells were purified and cultured on permeable support with and without keratinocyte growth factor (KGF). Messenger
Junji Miyabe et al.
Journal of pharmacological sciences, 139(3), 215-222 (2019-03-06)
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by amino acid
Ina Hubatsch et al.
Journal of medicinal chemistry, 50(21), 5238-5242 (2007-09-25)
The hPepT1-mediated transport properties of a series of 11 synthesized beta- and gamma-peptides have been studied in Caco-2 cells. The results show that several of the compounds interact with the peptide transporter, but only two beta-dipeptides act as substrates and
Jian Cang et al.
Drug metabolism and pharmacokinetics, 25(5), 500-507 (2010-09-30)
To investigate the pharmacokinetics and mechanism of intestinal absorption of JBP485 in rats, the pharmacokinetics of JBP485 were investigated in vivo both intravenously and orally. The effects of glycylsarcosine (Gly-Sar) on the uptake and transepithelial transport of JBP485 were examined

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