G8634
Guanosine 5′-[γ-thio]triphosphate tetralithium salt
≥90% (contains < 10% GDP, HPLC), powder
Synonym(s):
GTPγS tetralithium salt, GTP-γ-S-Li4, Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt
About This Item
Recommended Products
Quality Level
assay
≥90% (contains < 10% GDP, HPLC)
form
powder
color
white to off-white
solubility
H2O: ≥75 mg/mL (Solutions are very unstable; prepare immediately prior to use.)
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Li+].[Li+].[Li+].[Li+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C(=O)N1
InChI
1S/C10H16N5O13P3S.4Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-29(19,20)27-30(21,22)28-31(23,24)32;;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H,21,22)(H2,23,24,32)(H3,11,13,14,18);;;;/q;4*+1/p-4/t3-,5-,6-,9-;;;;/m1..../s1
InChI key
AMQXJFWJOAWCPV-ZVQJTLEUSA-J
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Related Categories
Application
- as a component of lysis buffer
- in oocyte and mammalian cell patch-clamp experiments to keep the G proteins in a constantly active state
- to couple with G- protein α, to study its effect on kinase activity
Biochem/physiol Actions
Features and Benefits
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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