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Key Documents

G9513

Sigma-Aldrich

γ-Globulins from goat

≥99% (agarose gel electrophoresis)

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

goat

Quality Level

assay

≥99% (agarose gel electrophoresis)

form

powder

impurities

2-4% NaCl

storage temp.

−20°C

General description

γ-Globulins are glycoproteins that are antibodies produced by plasma cells. They are immunoglobulins and exist in five classes, namely: IgG, IgM, IgA, IgD, and IgE. Immunoglobulins are heterogeneous molecules that constitute 20% of the plasma proteins. They are made up of four polypeptide chains (two light chains and two heavy chains) linked together by disulfide bonds. The antigen-binding site is present at the nitrogen terminal.

Biochem/physiol Actions

Immunoglobulins are generated in response to antigens, and they serve as key regulators of the immune system. They protect our bodies against bacteria, viruses, and fungi. Immunoglobulins are involved in the activation of the complement system, opsonization of microbes for phagocytosis, neutralization of toxins and viruses, and inhibition of the attachment of microbes to mucosal surfaces. Immunodeficiency can lead to recurrent infectious diseases.

Preparation Note

Prepared from Cohn Fraction II, III

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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[Postoperative thrombosis prevention using low-dose heparin].
A E Schaer et al.
Archiv fur Gynakologie, 219(1-4), 545-545 (1975-11-18)

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