MilliporeSigma
All Photos(1)

Documents

H0266

Sigma-Aldrich

Hemoglobin A2, Ferrous Stabilized human

lyophilized powder

Sign Into View Organizational & Contract Pricing

CAS Number:
EC Number:
MDL number:
eCl@ss:
42030116
NACRES:
NA.61

biological source

human

Quality Level

assay

97-100% (agarose gel electrophoresis)

form

lyophilized powder

technique(s)

immunofluorescence: suitable

suitability

suitable for electrophoresis and chromatography standard (has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... HBA2(3040)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
H0267H0392H7379
Hemoglobin human lyophilized powder

H7379

Hemoglobin human

assay

97-100% (agarose gel electrophoresis)

assay

97-100% (agarose gel electrophoresis)

assay

97-100% (agarose gel electrophoresis)

assay

-

biological source

human

biological source

human

biological source

human

biological source

human

suitability

suitable for electrophoresis and chromatography standard (has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).)

suitability

suitable for electrophoresis and chromatography standard (has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).)

suitability

suitable for electrophoresis and chromatography standard (has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).)

suitability

-

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Gene Information

human ... HBA2(3040)

Gene Information

human ... HBB(3043)

Gene Information

human ... HBB(3043)

Gene Information

human ... HBA1(3039), HBA2(3040), HBB(3043), HBD(3045), HBE1(3046), HBG1(3047), HBG2(3048), HBQ1(3049), HBZ(3050)

General description

Hemoglobin A2 (HBA2) is mapped to human chromosome 16p13.3. HBA2 is a minor hemoglobin component and comprises of two α and δ chains.
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.

Application

Hemoglobin A2 was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.
Hemoglobin A2, Ferrous Stabilized human has been used as a reference in reversed-phase high-performance liquid chromatography for quantifying δ-globin elution profile. It has also been used as calibrator in isotope dilution mass spectrometry (IDMS) measurements.

Biochem/physiol Actions

Elevated levels of Hemoglobin A2 (HBA2) is observed in patients with β-thalassemia trait.

Packaging

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Reconstitution

When reconstituted with buffer, gives >90% ferrous hemoglobin.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Elevated hemoglobin A2 as a marker for beta-thalassemia trait in pregnant women
Ou Z, et al.
The Tohoku Journal of Experimental Medicine, 223(3), 223-226 (2011)
Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies
Loucari C, et al.
Human Gene Therapy Methods, 29(1), 60-74 (2018)
Saqib Hussain Ansari et al.
JPMA. The Journal of the Pakistan Medical Association, 62(12), 1314-1317 (2013-07-23)
To screen immediate family members of thalassaemia patients for carrier identification and counselling. The cross-sectional study was conducted at an urban thalassaemia treatment and prevention centre in Karachi, Pakistan, from January to December 2008, and involved 188 siblings of 100
Alauddin Hafiza et al.
The Malaysian journal of pathology, 34(2), 161-164 (2013-02-22)
The capillary electrophoresis (CE) is a new system that utilizes the principle of electrokinetic separation of molecules in eight electrolyte buffer-filled silica capillaries. In this study, we established the normal ranges of haemoglobin A2 (HbA2) and haemoglobin F (HbF) levels
Domenico Dell'Edera et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 26(5), 445-448 (2012-10-09)
This research, conducted on 1495 couples in preconceptional period, demonstrates how the study of globular resistance of erythrocytes (GRO) is not a first choice test and not useful as other more accurate tests to identify subjects with β-thalassemia trait. Instead

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service