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H0501

Sigma-Aldrich

DL-Homocystine

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Synonym(s):
meso-4,4′-Dithio-bis(2-aminobutanoic acid)
Linear Formula:
HOOCCH(NH2)CH2CH2SSCH2CH2CH(NH2)COOH
CAS Number:
Molecular Weight:
268.35
Beilstein/REAXYS Number:
1728581
EC Number:
MDL number:
eCl@ss:
42021308
PubChem Substance ID:
NACRES:
NA.26

assay

≥98% (TLC)

Quality Level

form

powder

color

white to off-white

mp

>300 °C

application(s)

detection

SMILES string

N[C@H](CCSSCC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6+

InChI key

ZTVZLYBCZNMWCF-OLQVQODUSA-N

Gene Information

human ... BHMT(635)

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1 of 4

This Item
H5134H6010T2763
DL-Homocystine

H0501

DL-Homocystine

D-Homocystine

H5134

D-Homocystine

L-Homocystine ≥98% (HPLC)

H6010

L-Homocystine

Thymol iodide

T2763

Thymol iodide

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

-

color

white to off-white

color

white to off-white

color

white to off-white

color

-

mp

>300 °C

mp

-

mp

281-284 °C (dec.) (lit.)

mp

-

application(s)

detection

application(s)

-

application(s)

cell analysis
peptide synthesis

application(s)

diagnostic assay manufacturing
hematology
histology

Gene Information

human ... BHMT(635)

Gene Information

-

Gene Information

-

Gene Information

-

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Lei Li et al.
Amino acids, 50(10), 1485-1494 (2018-08-01)
Plasma homocysteine is elevated in patients with impaired renal function, and markedly so at end-stage renal disease. As chronic kidney disease and hyperhomocysteinemia are also independent risk factors for cardiovascular disease, the latter is hypothesized to accelerate vascular abnormalities following
Sezgin Bakirdere et al.
Analytica chimica acta, 680(1-2), 41-47 (2010-10-26)
An analytical method was developed for the determination of thiols in biological samples. Reverse phase chromatography coupled to ICP quadrupole MS or Orbitrap MS was employed for the separation and detection of thiols. For the determination of total thiols, oxidized
Javier Escobar et al.
Journal of pharmaceutical and biomedical analysis, 123, 104-112 (2016-02-20)
The aminothiols are biological compounds with numerous vital functions. One of the most relevant is their role as antioxidant systems. The reduced to oxidized ratios are extremely useful indicators of oxidative stress and cellular redox status. We have validated an
K Yokoi et al.
The Journal of nutrition, 131(4), 1302-1308 (2001-04-04)
The effect of dietary sulfur amino acids on bioelectric properties was studied in rats by using bioimpedance spectroscopy. Weanling rats were assigned to one of 12 groups in a factorially arranged experiment with dietary variables of supplemental sulfur amino acid
M W Orth et al.
The Journal of nutrition, 122(3), 482-487 (1992-03-01)
The effect of excessive levels of cysteine and homocysteine on tibial dyschondroplasia (TD) in broiler chicks was studied. In the first experiment, graded levels of L-cysteine as well as one level of L-homocysteine were supplemented to a corn-soybean-based diet adequate

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