H5534

trans-4-Hydroxy-L-proline

≥98.5%, suitable for cell culture, BioReagent

• Synonym(s): 4-Hydroxyproline, Hydroxyproline, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp
• Empirical Formula (Hill Notation): C₅H₉NO₃
• CAS Number: 51-35-4
• Molecular Weight: 131.13
• Beilstein/REAXYS Number: 81441
• EC Number: 200-091-9
• MDL number: MFCD00064320
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895700
• NACRES: NA.26

Properties

• product name: trans-4-Hydroxy-L-proline, BioReagent, suitable for cell culture, ≥98.5%
• product line: BioReagent
• assay: ≥98.5%
• form: crystalline
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: colorless
• mp: 273 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): peptide synthesis
• SMILES string: O[C@H]1CN[C@@H](C1)C(O)=O
• InChI: 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
• InChI key: PMMYEEVYMWASQN-DMTCNVIQSA-N

Description

Application

• Cysteine Radical and Glutamate Collaboratively Enable C-H Bond Activation and C-N Bond Cleavage in a Glycyl Radical Enzyme HplG.: This research showcases the application of trans-4-hydroxy-L-proline in studying enzymatic reactions that involve C-H bond activation and C-N bond cleavage, providing insights into the mechanisms of enzymatic control and specificity which are essential for the development of novel biochemical processes (Deng and Liao, 2024).


• Study on flavor quality formation in green and yellow tea processing by means of UPLC-MS approach.: Utilizing trans-4-hydroxy-L-proline, this study enhances the understanding of flavor biochemistry in tea processing, offering significant insights into the food chemistry sector and influencing future product development strategies (Sun et al., 2024).

Other Notes

Natural constituent of animal structural proteins such as collagen and elastin.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)