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Key Documents

HT60

Sigma-Aldrich

Amyloid Stain, Congo Red

Synonym(s):

Puchtler’s Modification for Amyloid

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About This Item

UNSPSC Code:
41116121
NACRES:
NA.47

shelf life

Expiry date on the label.

Quality Level

IVD

for in vitro diagnostic use

dilution

(for histology)

application(s)

hematology
histology

storage temp.

room temp

Principle

Amyloid protein is detected in tissue with Congo red, a metachromatic stain. Staining is intensified by pretreatment of tissue with alkaline sodium chloride.

Kit Components Only

Product No.
Description

  • Congo Red Solution (kit only) 500 mL

  • Sodium Chloride Solution, Alcoholic (kit only) 500 mL

  • Sodium Hydroxide Solution (kit only) 2 x 12

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

flash_point_f

57.2 °F - closed cup

flash_point_c

14.0 °C - closed cup


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Fubing Ouyang et al.
Brain pathology (Zurich, Switzerland), 30(1), 165-178 (2019-07-07)
Conflicting evidence exists regarding whether focal cerebral infarction contributes to cerebral amyloid-β (Aβ) deposition, as observed in Alzheimer's disease. In this study, we aimed to evaluate the presence of Aβ deposits in the ipsilateral thalamus and hippocampus 12 months post-stroke
Denise Herr et al.
Neurotoxicology, 84, 172-183 (2021-04-02)
Exposure to air pollution has been identified as a possible environmental contributor to Alzheimer's Disease (AD) risk. As the number of people with AD worldwide continues to rise, it becomes vital to understand the nature of this potential gene-environment interaction.
Laurence Ozmen et al.
Neuro-degenerative diseases, 2(6), 284-298 (2006-08-16)
Most of the transgenic mice generated to model Alzheimer's disease express human amyloid precursor protein (APP) mutants alone or in conjunction with presenilin mutants. We have generated a mouse model by overexpressing human BACE and human APP with the V717F
J Grayson Richards et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(26), 8989-9003 (2003-10-03)
Transgenic mice, expressing mutant beta-amyloid precursor proteins (betaAPPs), have lead to a better understanding of the pathophysiological processes in Alzheimer's disease (AD). In many of these models, however, the temporal development of cognitive decline and the relationship to Abeta deposition
Laurence Ozmen et al.
Neuro-degenerative diseases, 6(1-2), 29-36 (2008-12-11)
Alzheimer's disease is the most common cause of dementia occurring in the elderly. The identification of the genetic factors in the familial forms of the disease enabled the generation of transgenic animals which reproduce an essential part of its pathology.

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A stem cell culture protocol to generate 3D NSC models of Alzheimer’s disease using ReNcell human neural stem cell lines.

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