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L4395

Sigma-Aldrich

Liposome Kit: Lipid mixtures for the preparation of liposomes

lyophilized powder

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Synonym(s):
cholesterol, L-α-phosphatidylcholine and stearylamine kit
EC Number:
NACRES:
NA.25

biological source

egg yolk

Quality Level

form

lyophilized powder

composition

Cholesterol, 9 μmol/package
L-α-Phosphatidylcholine (egg yolk), 63 μmol/package
Stearylamine, 18 μmol/package

functional group

carboxylic acid

shipped in

ambient

storage temp.

−20°C

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This Item
L4754P5394P3556
form

lyophilized powder

form

powder

form

solid

form

lyophilized powder

composition

Cholesterol, 9 μmol/package , L-α-Phosphatidylcholine (egg yolk), 63 μmol/package , Stearylamine, 18 μmol/package

composition

-

composition

-

composition

-

functional group

carboxylic acid

functional group

-

functional group

phospholipid

functional group

phospholipid

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

Liposome Kit has been used for the preparation of liposomes.

Biochem/physiol Actions

Liposome Kit: Lipid mixtures for the preparation of liposomes contains cholesterol; L-α-phosphatidylcholine and stearylamine. Liposome kit may be used to prepare cationic (positively charge) liposomes for incorporation of materials into cells.
Liposomes can be used for different applications such as drug delivery, diagnostics, membrane models, adjuvants for vaccination and others. This lipid mixture can be used to encapsulate a broad spectrum of hydrophilic and amphipathic molecules of low, medium, and high molecular weight (including peptides, proteins, and oligo- and polynucleotides).

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Description
Pricing

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Giulietta Pinato et al.
Journal of biomedical optics, 16(9), 095001-095001 (2011-09-29)
Spatially confined and precise time delivery of neuroactive molecules is an important issue in neurophysiology. In this work we developed a technique for delivering chemical stimuli to cultured neurons consisting in encapsulating the molecules of interest in liposomes. These vectors
G T Köse et al.
Drug delivery, 5(4), 257-264 (1998-01-01)
Multilamellar vesicles (MLV) containing phosphatidyl choline (PC), cholesterol (CHOL), and stearylamine (SA) in the molar ratio of 7:2:0.2 were prepared by the thin film hydration method. Low-molecular-weight heparin (LMWH, MW: 3000) was conjugated with the MLV using carbodiimide (EDC). Infrared
Sub-Micrometric Liposomes as Drug Delivery Systems in the Treatment and Periodontitis
Di Turi G, et al.
International Journal of Immunopathology and Pharmacology, 25(3), 657-670 (2012)
Santosh Kumar et al.
JCI insight, 6(4) (2021-01-15)
Prime-boost immunization strategies are required to control the global tuberculosis (TB) pandemic, which claims approximately 3 lives every minute. Here, we have generated an immunogenic complex against Mycobacterium tuberculosis (M.tb), consisting of promiscuous T cell epitopes (M.tb peptides) and TLR
Xuan T A Nguyen et al.
Molecular neurobiology, 56(9), 6121-6133 (2019-02-08)
The cellular prion protein (PrPC), mainly known for its role in neurodegenerative diseases, is involved in several physiological processes including neuritogenesis. In addition, its ability to bind copper or zinc has been suggested for its role in metal homeostasis. Although

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