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Key Documents

L5502

Sigma-Aldrich

Lys-Lys dihydrochloride

≥98% (TLC)

Synonym(s):

Dilysine

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About This Item

Empirical Formula (Hill Notation):
C12H26N4O3 · 2HCl
CAS Number:
Molecular Weight:
347.28
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Lys-Lys dihydrochloride,

assay

≥98% (TLC)

form

powder

color

white

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

Cl.NCCCCC(N)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C12H26N4O3.ClH/c13-7-3-1-5-9(15)11(17)16-10(12(18)19)6-2-4-8-14;/h9-10H,1-8,13-15H2,(H,16,17)(H,18,19);1H

InChI key

ROGKVZGKYWMMAT-UHFFFAOYSA-N

Application

Lysyllysine (Lys-Lys) may be used in studies of prebiotically relevant Salt-Induced Peptide Formation (SIPF) and in for physical chemical analysis.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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S H Sleigh et al.
Biochemistry, 36(32), 9747-9758 (1997-08-12)
The periplasmic oligopeptide binding protein, OppA, acts as the initial receptor for the uptake of peptides by the oligopeptide permease (Opp) in Gram-negative bacteria. Opp will handle peptides between two and five amino acid residues regardless of their sequence. The
P Cosson et al.
European journal of cell biology, 73(2), 93-97 (1997-06-01)
Sec20p and Tip20p were previously identified as two interacting proteins involved in early steps of the secretory pathway in Saccharomyces cerevisiae. Here we describe a novel temperature-sensitive allele of TIP20 and analyze its phenotype. While sec20 and tip20 mutants exhibited
Jayasri Das Sarma et al.
The Journal of biological chemistry, 277(23), 20911-20918 (2002-04-04)
To define further the mechanisms of gap junction protein (connexin (Cx)) oligomerization without pharmacologic disruption, we have examined the transport and assembly of connexin constructs containing C-terminal di-lysine-based endoplasmic reticulum (ER) (HKKSL) or ER-Golgi intermediate compartment (AKKFF) targeting sequences. By
D Nurizzo et al.
Biochemistry, 40(6), 1616-1623 (2001-05-01)
Human transferrin (Tf) is responsible for the binding and transport of iron in the bloodstream of vertebrates. Delivery of this bound iron to cells occurs by a process of receptor-mediated endocytosis during which Tf releases its iron at the reduced
F L Henriquez et al.
Parasitology, 131(Pt 2), 169-179 (2005-09-10)
Studies using antibodies to immunolocalize the Toxoplasma gondii dense granule protein GRA3, have shown that this protein associates strongly with the parasitophorous vacuole membrane (PVM). However, as there was no predicted membrane-spanning domain this highlighted an unanswered paradox. We demonstrate

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