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L9151

Sigma-Aldrich

Lys-Lys-Lys-Lys-Lys

≥55% peptide basis

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Synonym(s):
Lys5, Pentalysine
Empirical Formula (Hill Notation):
C30H62N10O6
CAS Number:
Molecular Weight:
658.88
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

form

powder

composition

Peptide content, ~60%

concentration

≥55% (peptide)

color

white

storage temp.

−20°C

SMILES string

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)

InChI key

IXPHOHNWDLRFJH-UHFFFAOYSA-N

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1 of 4

This Item
L9026L8901L5502
Lys-Lys-Lys-Lys-Lys ≥55% peptide basis

L9151

Lys-Lys-Lys-Lys-Lys

Lys-Lys-Lys-Lys ≥95% (TLC)

L9026

Lys-Lys-Lys-Lys

Lys-Lys-Lys ≥97% (TLC)

L8901

Lys-Lys-Lys

Lys-Lys dihydrochloride

L5502

Lys-Lys dihydrochloride

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

color

white

color

white

color

white to off-white

color

white

composition

Peptide content, ~60%

composition

Peptide content, ≥50%

composition

Peptide content, ~60%

composition

-

concentration

≥55% (peptide)

concentration

-

concentration

-

concentration

-

Amino Acid Sequence

Lys-Lys-Lys-Lys

Biochem/physiol Actions

Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Seiichi Okabe et al.
Experimental hematology & oncology, 10(1), 19-19 (2021-03-06)
Multiple myeloma (MM) is a type of hematological malignancy affecting the functions of plasma cells. The treatment of MM patients has changed dramatically with the use of new agents. However, unfortunately, it is still incurable. Therefore, a new approach for
M Mosior et al.
Biochimica et biophysica acta, 1105(1), 185-187 (1992-03-23)
The binding of pentalysine to phospholipid vesicles depends in a sigmoidal manner on the mole fraction of acidic lipid in the vesicles. A simple analysis demonstrates that this apparent cooperativity is probably due to both the reduction of dimensionality that
J H Kleinschmidt et al.
Biophysical journal, 73(5), 2546-2555 (1997-11-25)
The interactions of lysine oligopeptides with dimyristoyl phosphatidylglycerol (DMPG) bilayer membranes were studied using spin-labeled lipids and electron spin resonance spectroscopy. Tetralysine and pentalysine were chosen as models for the basic amino acid clusters found in a variety of cytoplasmic
Fabiana Perocchi et al.
Nucleic acids research, 35(19), e128-e128 (2007-09-28)
Recent transcription profiling studies have revealed an unanticipatedly large proportion of antisense transcription across eukaryotic and bacterial genomes. However, the extent and significance of antisense transcripts is controversial partly because experimental artifacts are suspected. Here, we present a method to
Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids.
T M Lohman et al.
Biochemistry, 19(15), 3522-3530 (1980-07-22)

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