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MAK068

Sigma-Aldrich

MPO Colorimetric Activity Assay Kit

sufficient for 100 colorimetric tests

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Synonym(s):
Myeloperoxidase Colorimetric Activity Assay Kit
NACRES:
NA.84

usage

sufficient for 100 colorimetric tests

detection method

colorimetric

relevant disease(s)

cancer; cardiovascular diseases; hematological disorder

storage temp.

−20°C

Gene Information

human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)

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MAK114

Glyoxalase I Activity Assay Kit

Mouse MPO ELISA Kit for plasma and cell culture supernatant

RAB0374

Mouse MPO ELISA Kit

usage

sufficient for 100 colorimetric tests

usage

sufficient for 100 colorimetric tests

usage

sufficient for 100 tests (UV)

usage

-

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

relevant disease(s)

cancer; cardiovascular diseases; hematological disorder

relevant disease(s)

gastrointestinal diseases; cardiovascular diseases

relevant disease(s)

cancer

relevant disease(s)

-

General description

Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.

Application

MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.

Features and Benefits

Compatible with high-throughput handling systems.

Suitability

Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells

Principle

In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

188.6 °F

flash_point_c

87 °C


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