MAK068
MPO Colorimetric Activity Assay Kit
sufficient for 100 colorimetric tests
Synonym(s):
Myeloperoxidase Colorimetric Activity Assay Kit
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
Product Name
MPO Colorimetric Activity Assay Kit, sufficient for 100 colorimetric tests
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer; cardiovascular diseases; hematological disorder
storage temp.
−20°C
Gene Information
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
Application
MPO Colorimetric Activity Assay Kit has been used to determine the activity of myeloperoxidase in samples.
Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells
Biochem/physiol Actions
In this assay, MPO catalyzes the formation of hypochlorous acid, which reacts with taurine to form taurine chloroamine. Taurine chloroamine reacts with the chromophore TNB, resulting in the formation of the colorless product DTNB. One unit of MPO activity is defined as the amount of enzyme that hydrolyzes the substrate and generates taurine chloramine to consume 1.0 μmole of TNB per minute at 25 °C.
Features and Benefits
Compatible with high-throughput handling systems.
General description
Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypochlorous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
flash_point_f
188.6 °F
flash_point_c
87 °C
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