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MAK132

Sigma-Aldrich

Sulfate Assay Kit

sufficient for 200 tests (turbidimetric)

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NACRES:
NA.84

usage

sufficient for 200 tests (turbidimetric)

detection method

turbidimetric

relevant disease(s)

genitourinary disorders

storage temp.

room temp

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MAK366MAK276MAK335
Sulfate Assay Kit sufficient for 200 tests (turbidimetric)

MAK132

Sulfate Assay Kit

Succinate Assay Kit sufficient for 100 colorimetric or fluorometric tests

MAK335

Succinate Assay Kit

usage

sufficient for 200 tests (turbidimetric)

usage

sufficient for 100 colorimetric tests

usage

-

usage

sufficient for 100 colorimetric or fluorometric tests

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

relevant disease(s)

genitourinary disorders

relevant disease(s)

pulmonary disorders

relevant disease(s)

cancer

relevant disease(s)

cardiovascular diseases; immunological diseases

General description

Inorganic sulfate is one of the most abundant anions in mammalian plasma. Sulfate plays important physiological roles in activating and detoxifying xenobiotics, steroids, neurotransmitters, and bile acids. Sulfate is needed for the biosynthesis of cerebroside sulfate, glycosaminoglycans, and heparin sulfate. Undersulfation of cartilage proteoglycans has been associated with human inherited osteochondro-dysplasia disorders. In mammals, sulfate homeostasis is regulated by the kidney. The majority of filtered sulfate is absorbed in the proximal tubules and only 5-20% of the filtered load is excreted into the urine.

Application

Sulfate Assay Kit has been used to determine the concentration of sulfate.

Features and Benefits

Compatible with high-throughput handling systems. Can be adapted for use with cuvettes.

Suitability

Suitable for the detection of sulfate in biological fluids such as serum and urine.

Principle

The kit employs an improved method utilizes the quantitative formation of insoluble barium sulfate in polyethylene glycol. The turbidity measured at 600 nm is proportional to sulfate level in the sample.

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 2


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Physiological Roles and Regulation of Mammalian Sulfate Transporters.
Daniel M.
Physiological Reviews, 81(4) (2001)
Partial deletion of the sulfate transporter SLC13A1 is associated with an osteochondrodysplasia in the Miniature Poodle breed.
Neff M W, et al.
PLoS ONE, 7(12), e51917-e51917 (2012)
Transcriptional regulation of the sodium-sulfate cotransporter NaSi-1 gene.
Dawson P A and Daniel M
Cell Biochemistry and Biophysics, 36(2-3), 175-182 (2002)
Niklas Wahlström et al.
Carbohydrate polymers, 233, 115852-115852 (2020-02-16)
The cell wall polysaccharide ulvan was isolated from two species of the seaweed Ulva collected along the Swedish west coast. Acidic extraction was benchmarked against hot water extraction with enzymatic purification and against commercial ulvan. Extracted ulvan contained 11-18 %
Molecular aspects of renal tubular handling and regulation of inorganic sulfate.
Beck L and Caroline S
Kidney International, 59(3), 835-845 (2001)

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