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Key Documents

N0877

Sigma-Aldrich

4-Nitrophenyl α-D-galactopyranoside

α-glucosidase substrate, chromogenic, ≥99% (TLC), powder

Synonym(s):

p-Nitrophenyl α-D-galactopyranoside

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About This Item

Empirical Formula (Hill Notation):
C12H15NO8
CAS Number:
Molecular Weight:
301.25
Beilstein/REAXYS Number:
92214
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

4-Nitrophenyl α-D-galactopyranoside, α-galactosidase substrate

assay

≥99% (TLC)

form

powder

solubility

methanol: 100 mg/mL, clear to very slightly hazy

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9+,10+,11-,12+/m1/s1

InChI key

IFBHRQDFSNCLOZ-IIRVCBMXSA-N

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Application

4-Nitrophenyl α-D-galactopyranoside has been used as a substrate to determine α-galactosidase activity.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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This experiment was designed to synthesize 18 kinds of polyhydroxybenzophenones by using Friedel-Crafts reaction, and to measure the inhibitory activity on α-glucosidase with p-nitrophenyl-β-D-galactopyranoside (PNPG) as a substrate. Here, acarbose (IC(50)  = 1674.75 µmol L(-1) ) was used as the reference

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