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P3657

Sigma-Aldrich

Pyridoxal 5′-phosphate hydrate

powder, BioReagent, suitable for cell culture

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Synonym(s):
3-Hydroxy-2-methyl-5-([phosphonooxy]methyl)-4-pyridinecarboxaldehyde, Codecarboxylase, PLP, Pyridoxal 5-phosphate
Empirical Formula (Hill Notation):
C8H10NO6P · xH2O
CAS Number:
Molecular Weight:
247.14 (anhydrous basis)
Beilstein/REAXYS Number:
234749
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

product line

BioReagent

assay

≥98%

form

powder

mol wt

Mw 247.14 g/mol

technique(s)

cell culture | mammalian: suitable

color

off-white to yellow-brown

mp

140-143 °C

solubility

1 M HCl: soluble 50 mg/mL, clear, colorless to light yellow-green

storage temp.

−20°C

SMILES string

CC1=NC=C(COP(O)(O)=O)C(C([H])=O)=C1O

InChI

1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChI key

NGVDGCNFYWLIFO-UHFFFAOYSA-N

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1 of 4

This Item
P925582870P6155
vibrant-m

P3657

Pyridoxal 5′-phosphate hydrate

Essential+ Grade
vibrant-m

P9255

Pyridoxal 5′-phosphate hydrate

-
vibrant-m

82870

Pyridoxal 5′-phosphate monohydrate

-
vibrant-m

P6155

Pyridoxal hydrochloride

Essential+ Grade
technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable

technique(s)

enzyme immunoassay: suitable

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

color

off-white to yellow-brown

color

beige, off-white to yellow

color

white to light yellow

color

white to off-white

mp

140-143 °C

mp

140-143 °C

mp

140-143 °C (lit.)

mp

173 °C (dec.) (lit.)

General description

Pyridoxal-phosphate (PLP, pyridoxal-5′-phosphate, P5P) is a prosthetic group of some enzymes. It is the active form of vitamin B6, which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of host cells and in enabling the parasite to escape the human immune response. To explore this potential drug target, we have synthesized a small library of
Trina Das et al.
The Journal of general virology, 96(Pt 2), 294-310 (2014-10-30)
Chikungunya virus (CHIKV) has recently affected millions of people in the Indian Ocean, with rare cases of encephalopathy and encephalitis occurring in neonates. In the study described herein, the capacity of mouse brain cells to control infection through innate immune
Jennifer H Richens et al.
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Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behavioral deficits. Here, we show that Drosophila mutants in the homolog of

Articles

This page segues to comprehensive insights on how Vitamin B6, Pyridoxal and Pyridoxine affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of pyridoxal, pyridoxine.

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