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P6280

Sigma-Aldrich

Pyridoxine hydrochloride

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

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Synonym(s):
Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride
Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
Molecular Weight:
205.64
Beilstein:
3632435
EC Number:
MDL number:
eCl@ss:
34058008
PubChem Substance ID:
NACRES:
NA.21

product line

BioReagent

Quality Level

Assay

≥98% (HPLC)

form

powder

mol wt

Mw 205.64 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

color

white to off-white

mp

214-215 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

application(s)

agriculture

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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1 of 4

This Item
P4722BP458P9755
Pyridoxine hydrochloride BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Sigma-Aldrich

P6280

Pyridoxine hydrochloride

Essential+ Grade
Pyridoxine hydrochloride meets USP testing specifications

Sigma-Aldrich

P4722

Pyridoxine hydrochloride

-
Pyridoxine hydrochloride British Pharmacopoeia (BP) Reference Standard

BP458

Pyridoxine hydrochloride

-
Pyridoxine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

P9755

Pyridoxine hydrochloride

-
form

powder

form

powder

form

solid

form

powder

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable

color

white to off-white

color

white

color

white

color

white to off-white

mp

214-215 °C (lit.)

mp

214-215 °C (lit.)

mp

214-215 °C (lit.)

mp

214-215 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

General description

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate. 

Application

Pyridoxine hydrochloride has been used:
  • as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
  • as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
  • as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem/physiol Actions

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
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25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Vitamin B6, Pyridoxal and Pyridoxine in Cell Culture

This page segues to comprehensive insights on how Vitamin B6, Pyridoxal and Pyridoxine affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of pyridoxal, pyridoxine.

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