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P5669

Sigma-Aldrich

Pyridoxine

≥98%

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Synonym(s):
Pyridoxol, Vitamin B6
Empirical Formula (Hill Notation):
C8H11NO3
CAS Number:
Molecular Weight:
169.18
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

Assay

≥98%

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

159-162 °C (lit.)

SMILES string

Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3

InChI key

LXNHXLLTXMVWPM-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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This Item
P9755P4722705322
Pyridoxine ≥98%

Sigma-Aldrich

P5669

Pyridoxine

form

powder

form

powder

form

powder

form

powder

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

color

white to off-white

color

white

color

white to off-white

mp

159-162 °C (lit.)

mp

214-215 °C (lit.)

mp

214-215 °C (lit.)

mp

224-226 °C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

General description

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.
Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B6 is distributed in nuts, whole grains and animal meat.

Application

Pyridoxine has been used as a component of:
  • artificial diet for sugarcane aphid pest
  • modified Strullu and Romand (MSR) medium for carrot root organ culture
  • Luria broth for E coli cultures

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.

Biochem/physiol Actions

Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B6 leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T1503
Product Number
-
25G
Pack Size/Quantity

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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Tracking Lipid Transfer by Fatty Acid Isotopolog Profiling from Host Plants to Arbuscular Mycorrhiza Fungi
Redkar A, et al.
Bio-protocol, 8(7) (2018)
E B Rimm et al.
JAMA, 279(5), 359-364 (1998-02-12)
Hyperhomocysteinemia is caused by genetic and lifestyle influences, including low intakes of folate and vitamin B6. However, prospective data relating intake of these vitamins to risk of coronary heart disease (CHD) are not available. To examine intakes of folate and
Simultaneous high performance liquid chromatographic analysis of vitamins B1, B2 and B6 in royal jelly
Ana Elisa Presoto
Journal of the Brazilian Chemical Society, 15(1), 136-139 (2004)
Seizures caused by pyridoxine (vitamin B6) deficiency in adults: A case report and literature review
Tong Y
Intractable & rare diseases research, 3(2), 52-56 (2014)
An artificial diet for the sugarcane aphid (Melanaphis sacchari Zehntner)(Hemiptera: Aphididae) with potential uses for in vitro toxicological studies
Toledo-Hernandez E, et al.
Florida entomologist, 101(3), 395-399 (2018)

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