F8758

Folic acid

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥97%

• Synonym(s): Pterylmonoglutamic acid, PteGlu, Pteroyl-L-glutamic acid, Vitamin M
• Empirical Formula (Hill Notation): C₁₉H₁₉N₇O₆
• CAS Number: 59-30-3
• Molecular Weight: 441.40
• Beilstein/REAXYS Number: 100781
• EC Number: 200-419-0
• MDL number: MFCD00079305
• UNSPSC Code: 12352205
• eCl@ss: 34058014
• PubChem Substance ID: 24894973
• NACRES: NA.75

Properties

• biological source: synthetic
• Quality Level: 300
• product line: BioReagent
• assay: ≥97%
• form: powder
• mol wt: M_w 441.40 g/mol
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• color: dark yellow
• solubility: 1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, faintly yellow to dark yellow-orange
• storage temp.: room temp
• SMILES string: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChI key: OVBPIULPVIDEAO-LBPRGKRZSA-N

Description

General description

Folic acid (FA)/pterylmonoglutamic acid helps to block neural tube defects (NTDs).

Application

Folic acid has been used:

• to study the role of vitamins and amino acids on hybridoma growth and monoclonal antibody production
• in cells and treatments
• in perforin gene targeting using the CRISPR/Cas gene editing approach

Biochem/physiol Actions

A nutritional delivery form of folate. Folic acid and its derivatives are essential mediators of one-carbon metabolism within cells.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)