MilliporeSigma
All Photos(2)

Documents

RAB0273

Sigma-Aldrich

Human IL-1 β ELISA Kit

for serum, plasma, cell culture supernatant and urine

Sign Into View Organizational & Contract Pricing

Synonym(s):
Il-1 beta, Interleukin-1 beta

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 pg/mL
standard curve range: 0.48-100 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL1B(3553)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
RAB0269RAB0279RAB0283
Human IL-1 &#946; ELISA Kit for serum, plasma, cell culture supernatant and urine

RAB0273

Human IL-1 β ELISA Kit

Human IL-1 &#945; ELISA Kit for serum, plasma, cell culture supernatant and urine

RAB0269

Human IL-1 α ELISA Kit

Sigma-Aldrich

RAB0279

Human IL-1 sRI ELISA Kit

Human IL-1ra ELISA Kit for serum, plasma, cell culture supernatant and urine

RAB0283

Human IL-1ra ELISA Kit

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.3 pg/mL
standard curve range: 0.48-100 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.5 pg/mL
standard curve range: 0.412-300 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 8.19-2000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 100 pg/mL
standard curve range: 0.124-30 ng/mL

input

sample type urine
sample type serum
sample type plasma
sample type cell culture supernatant(s)

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine

input

sample type plasma
sample type urine
sample type serum
sample type cell culture supernatant(s)

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

technique(s)

ELISA: suitable, capture ELISA: suitable

packaging

kit of 96 wells (12 strips x 8 wells)

packaging

kit of 96 wells (12 strips x 8 wells)

packaging

kit of 96 wells (12 strips x 8 wells)

packaging

kit of 96 wells (12 strips x 8 wells)

General description

The Human IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-1 β in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human IL-1β

Application

For research use only. Not for use in diagnostic procedures.
Human IL-1 β ELISA kit has been used to measure the concentration of interleukin 1β (IL-1 β) in cell culture supernatants.

Biochem/physiol Actions

Interleukin 1β (IL-1 β) is a proinflammatory cytokine, which is implicated in induction of various acute and chronic inflammation. Hence, IL1B can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1β protein increases the production of endogenous 92kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). Elevated concentration of IL-1β in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. IL-1β brings neutrophil and macrophage to the site of infection. Mutations in IL-1β gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders.
Takahashi T
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 85(2), 135-141 (1998)
Zhao Gao et al.
BMC ophthalmology, 20(1), 134-134 (2020-04-08)
Inflammation of RPE cells led to different kinds of eye diseases and affected the normal function of the retina. Furthermore, higher levels of ROCK1 and ROCK2 induced injury of endothelial cells and many inflammatory diseases of the eyes. Ripasudil, which
Zetao Ma et al.
Journal of orthopaedic surgery and research, 15(1), 284-284 (2020-07-30)
Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) can induce the occurrence and development of autophagy.
Jie Liu et al.
The Journal of international medical research, 49(3), 300060521996564-300060521996564 (2021-03-27)
Porphyromonas gingivalis (Pg) plays a critical role in the occurrence and development of atherosclerosis. Lipopolysaccharide from Pg (Pg-LPS) could lead to pyroptosis of vascular smooth muscle cells (VSMCs) and induce instability of atherosclerotic plaque. Therefore, pyroptosis of VSMCs could promote
Hui Huang et al.
Annals of translational medicine, 9(18), 1460-1460 (2021-11-05)
Pancreatic cancer (PC) is one of the worst prognostic cancers. Here, we probed the anti-cancer activity of wogonoside (Wog), a flavonoid isolated from Scutellaria baicalensis Georgi, on PC, as well as potential molecular mechanism. Following Wog stimulation, the viability, proliferation

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service