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S6021

Sigma-Aldrich

D-Sorbitol

≥98% (GC), Molecular Biology

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
50-70-4
Molecular Weight:
182.17
Beilstein/REAXYS Number:
1721899
EC Number:
200-061-5
MDL number:
MFCD00004708
UNSPSC Code:
12352201
PubChem Substance ID:
24899683
NACRES:
NA.31
Pricing and availability is not currently available.

grade

Molecular Biology

Quality Level

200

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

≥98% (GC)

form

powder or crystals

color

white

useful pH range

5.0-7 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: soluble 182g/l at 20 °C (68 °F)

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Insulin-like Growth Factor-I Receptor human &#8805;95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

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Insulin-like Growth Factor-I Receptor human

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥95% (HPLC)

assay

≥98% (SDS-PAGE and HPLC)

assay

≥95% (HPLC)

assay

≥95% (SDS-PAGE)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in NSO cells

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Application

May be used for washing spheroplasts[1] and in isoelectric focusing to minimize endoosmotic flow in agarose gels.[2] May be used to induce osmotic stress.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM9016
    0000425480
    0000425480
    0000410943
    0000410941

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    Isoelectric focusing.
    D E Garfin
    Methods in enzymology, 182, 459-477 (1990-01-01)
    Arlene E Dent et al.
    PloS one, 3(10), e3557-e3557 (2008-10-30)
    Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays
    Kartik A Shah et al.
    Biotechnology and bioengineering, 112(12), 2624-2629 (2015-06-03)
    Monoclonal antibodies (mAbs) that bind and neutralize human pathogens have great therapeutic potential. Advances in automated screening and liquid handling have resulted in the ability to discover antigen-specific antibodies either directly from human blood or from various combinatorial libraries (phage
    Youngkook Kwon et al.
    ChemSusChem, 6(3), 455-462 (2013-01-25)
    This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction
    J M van Griensven et al.
    Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)
    To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat
    View All Related Papers

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