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S8701

Sigma-Aldrich

SFLLR-NH2 trifluoroacetate salt

≥95% (HPLC), powder

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Synonym(s):
L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-Arginine amide trifluoroacetate salt, Ser-Phe-Leu-Leu-Arg-amide trifluoroacetate salt, Thrombin Receptor Activator for Peptide 5 (TRAP-5) trifluoroacetate salt
Empirical Formula (Hill Notation):
C30H51N9O6 · xC2HF3O2
Molecular Weight:
633.78 (free base basis)
MDL number:
PubChem Substance ID:

Quality Level

assay

≥95% (HPLC)

form

powder

color

white to off-white

solubility

H2O: ≥2 mg/mL

storage temp.

−20°C

SMILES string

OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI

1S/C30H51N9O6.C2HF3O2/c1-17(2)13-22(27(43)36-21(25(32)41)11-8-12-35-30(33)34)38-28(44)23(14-18(3)4)39-29(45)24(37-26(42)20(31)16-40)15-19-9-6-5-7-10-19;3-2(4,5)1(6)7/h5-7,9-10,17-18,20-24,40H,8,11-16,31H2,1-4H3,(H2,32,41)(H,36,43)(H,37,42)(H,38,44)(H,39,45)(H4,33,34,35);(H,6,7)/t20-,21-,22-,23-,24-;/m0./s1

InChI key

UUNMFWMQJXBTAA-VHIJBDTGSA-N

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This Item
T7830SML1460H3042
SFLLR-NH2 trifluoroacetate salt ≥95% (HPLC), powder

S8701

SFLLR-NH2 trifluoroacetate salt

TFLLR-NH2 trifluoroacetate salt >98% (HPLC)

T7830

TFLLR-NH2 trifluoroacetate salt

Hemopressin trifluoroacetate salt ≥98% (HPLC), powder

H3042

Hemopressin trifluoroacetate salt

assay

≥95% (HPLC)

assay

>98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: ≥2 mg/mL

solubility

H2O: >2 mg/mL

solubility

-

solubility

H2O: ≥2 mg/mL

color

white to off-white

color

white to tan

color

white to off-white

color

white to off-white

Application

SFLLR-NH2 trifluoroacetate salt may be used in cell signaling and immunology studies.

Biochem/physiol Actions

SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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