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Key Documents

SAB1305546

Sigma-Aldrich

MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse

clone 8H10D10, IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

ACTB, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed, Beta-actin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

8H10D10, monoclonal

form

buffered aqueous solution

mol wt

41737 Da

species reactivity

human

technique(s)

immunohistochemistry: 1:10-1:50
western blot: 1:2000-1:10000

NCBI accession no.

NP_001092.1

UniProt accession no.

P60709

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ACTB(60)

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Angelo Di Vincenzo et al.
Diabetes, metabolic syndrome and obesity : targets and therapy, 16, 1885-1893 (2023-06-29)
Psoriasis is a chronic systemic inflammatory disease involving the production of many pro-inflammatory cytokines derived from immune cells and interacting with different tissues leading to the typical skin lesions. Psoriasis shows a higher prevalence and a worse progression in obese
Breanna Cole-Skinner et al.
Frontiers in cell and developmental biology, 12, 1348707-1348707 (2024-08-05)
Background: Cancer cell evasion of the immune response is critical to cancer development and metastases. Clinicians' ability to kickstart the immune system to target these rogue cells is an ever-growing area of research and medicine. This study delved into the
Yichen Zhao et al.
Cell death & disease, 15(6), 399-399 (2024-06-08)
The loss of dopaminergic neurons in the substantia nigra is a hallmark of pathology in Parkinson's disease (PD). Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) is the critical enzyme responsible for the degradation of asymmetric dimethylarginine (ADMA) which inhibits nitric oxide (NO) synthase and
Alicia Arredondo Eve et al.
Nutrients, 12(9) (2020-08-23)
Diet and lifestyle choices contribute to obesity and liver disease. Broccoli, a brassica vegetable, may mitigate negative effects of both diet and lifestyle. Currently, there are no clinically relevant, established molecular biomarkers that reflect variability in human absorption of brassica
Eylem Kulkoyluoglu-Cotul et al.
Cancers, 11(4) (2019-04-17)
A majority of breast cancer specific deaths in women with ERα (+) tumors occur due to metastases that are resistant to endocrine therapy. There is a critical need for novel therapeutic approaches to resensitize recurrent ERα (+) tumors to endocrine
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