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SAB5500056

Sigma-Aldrich

Anti-CD278/ICOS antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP98, affinity isolated antibody

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Synonym(s):
Anti-AILIM, Anti-CD278, Anti-CVID1
NACRES:
NA.41

biological source

rabbit

Quality Level

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP98, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

rat

technique(s)

immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... ICOS(29851)

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SAB56000311SAB1306778SAB1401658
Gene Information

human ... ICOS(29851)

Gene Information

human ... ICOS(29851)

Gene Information

human ... ICOS(29851)

Gene Information

human ... ICOS(29851)

antibody form

affinity isolated antibody

antibody form

affinity purified immunoglobulin

antibody form

IgG fraction of antiserum

antibody form

purified immunoglobulin

biological source

rabbit

biological source

-

biological source

rabbit

biological source

rabbit

clone

SP98, monoclonal

clone

RM417, monoclonal

clone

polyclonal

clone

polyclonal

species reactivity

human (tested)

species reactivity

human

species reactivity

human

species reactivity

human

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General description

CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

Immunogen

Synthetic peptide corresponding to C-terminus of human CD278.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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