SAE0091
Lysostaphin from Staphylococcus staphylolyticus
free of DNA contaminants, ≥500 units/mg protein, lyophilized powder, suitable for Microbiome research
Synonym(s):
Lysostaphin from Staphylococcus staphylolyticus, Glycyl-glycine Endopeptidase
About This Item
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product name
Lysostaphin from Staphylococcus staphylolyticus, free of DNA contaminants, suitable for Microbiome research, lyophilized powder, ≥500 units/mg protein
biological source
microbial (Staphylococcus staphylotyticus)
form
lyophilized powder
specific activity
≥500 units/mg protein
mol wt
27 kDa
feature
DNA free
shipped in
wet ice
Storage temp.
−20°C
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Application
Lysostaphin is a zinc metalloenzyme isolated from a bacterial culture of Staphylococcus staphylolyticus. It has specific lytic action against other Staphylococcus species, including S. aureus.1,2 Lysostaphin has
hexosaminidase, amidase, and endopeptidase activities. It cleaves polyglycine crosslinks in the cellular wall which leads to cell lysis of Staphylococcus species, but not of other bacterial genera. [Pharmaceuticals 2010, 3(4), 1139-1161]
Lysostaphin is a single polypeptide chain of 246 amino acids, a molecular mass of 26,926 Da, isoelectric point of 9.5, (5) and an activity pH optimum of 7.5.(6)
Biochem/physiol Actions
pH Optimum for activity: ~7.5
Unit Definition
Physical form
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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