SCP0054
Endothelin Big 1-38 human
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About This Item
Empirical Formula (Hill Notation):
C189H282N48O56S5
Molecular Weight:
4282.87
NACRES:
NA.32
UNSPSC Code:
12352200
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Application
Endothelin Big (1-38) is the precursor of Endothelin 1. [D-Val22]-Endothelin-1 Big fragment (16-38) is used to inhibit endothelin-converting enzyme activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Marie-Hélène Fecteau et al.
Hypertension (Dallas, Tex. : 1979), 46(1), 87-92 (2005-06-16)
The precursor of endothelin-1, big endothelin-1, can be hydrolyzed by chymase to generate endothelin-1 (1-31) in vitro. In the present study, we explored the processes involved in the production of endothelin-1 (1-31) as well as its pharmacodynamic characteristics in the
Michael Zimmermann et al.
Neurosurgical review, 26(2), 125-132 (2003-09-10)
The aim of this study was to investigate whether the blocking of endothelin-converting enzyme (ECE) activity offers a new approach to inhibiting the development of cerebral vasospasm after subarachnoid hemorrhage (SAH) by preventing transformation of big endothelin-1 (big ET-1) to
G C Hanson et al.
Regulatory peptides, 68(1), 63-69 (1997-01-15)
The hydrolysis of human big endothelin 1-38 (bigET-1) was investigated in the membrane fractions from three human lung specimens. The hydrolysis products were identified by HPLC or by amino acid analysis, peptide sequencing and mass spectrometry, and the contractile effects
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SCP0054-500UG | 04061833015506 |
| SCP0054-1MG | 04061826693315 |