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assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥65%
storage condition
protect from light
storage temp.
−20°C
Amino Acid Sequence
Thr-Phe-Leu-Leu-Arg-NH2
Application
PAR-1 selective agonist has been used for platelet aggregation.
Thr-Phe-Leu-Leu-Arg-NH2 (TFLLR-NH2) is used as a selective agonist for protease-activated receptor 1 (PAR1) which is involved in the development of cardiac remodeling and hypertrophy after myocardial injury.
Biochem/physiol Actions
Protease-activated receptor-1 (PAR-1) is a G protein-coupled receptor, that is activated through thrombin and other proteases.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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