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SMB00285

Sigma-Aldrich

Glucose-Udp-Fluorescein Conjugate

≥95% (HPLC)

Synonym(s):

Glucose-UDP-Fluorescein Conjugate, Glucose-Uridine Diphosphate, Glucose-Uridine Diphosphate-(PEG)6-Fluorescein Conjugate, UDP-Glc-(PEG)6-Fluorescein Conjugate

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About This Item

UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.28

conjugate

fluorescein conjugate

assay

≥95% (HPLC)

form

solid

color

orange-brown, solid

fluorescence

λex 490 nm; λem 514 nm

storage temp.

−20°C

SMILES string

O[C@@H]1[C@@H](O)[C@H](OP(OP([O-])(OC[C@H]2O[C@@H](N(C=C3/C=C/CNC(C4=CC=C(C([O-])=O)C(C(C5=C(O6)C=C(O)C=C5)=C7C6=CC(C=C7)=O)=C4)=O)C(NC3=O)=O)[C@H](O)[C@@H]2O)=O)([O-])=O)O[C@H](CO)[C@H]1O.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC

InChI

1S/C39H39N3O23P2.3C6H15N/c43-14-26-29(46)31(48)33(50)38(63-26)64-67(58,59)65-66(56,57)60-15-27-30(47)32(49)36(62-27)42-13-17(35(52)41-39(42)55)2-1-9-40-34(51)16-3-6-20(37(53)54)23(10-16)28-21-7-4-18(44)11-24(21)61-25-12-19(45)5-8-22(25)28;3*1-4-7(5-2)6-3/h1-8,10-13,26-27,29-33,36,38,43-44,46-50H,9,14-15H2,(H,40,51)(H,53,54)(H,56,57)(H,58,59)(H,41,52,55);3*4-6H2,1-3H3/b2-1+;;;/t26?,27-,29-,30-,31-,32-,33?,36-,38+;;;/m1.../s1

InChI key

ZANXKXSOYBZRQT-VBPZYQLFSA-N

Biochem/physiol Actions

Glucose-UDP, or UDP-Glucose, is a nucleotide sugar that plays a key role in carbohydrate metabolism. UDP-Glucose is a precursor to glycogen and a key substrate for glycosyltransferases, such as Toxins A and B from Clostridium difficile. Fluorescent analogs of UDP-Glucose can be used for studying glucosyltransferases and clostridial toxins. This fluorescein UDP-Glucose derivative has spectral properties identical to those of FITC conjugates. Compared to SMB00284, this UDP-Glucose derivative has a much shorter spacer between the fluorophore and UDP moiety.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Philippe Jean et al.
Nature communications, 11(1), 3208-3208 (2020-06-27)
Inner hair cells (IHCs) are the primary receptors for hearing. They are housed in the cochlea and convey sound information to the brain via synapses with the auditory nerve. IHCs have been thought to be electrically and metabolically independent from

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