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10127647001

Roche

Glucose-6-phosphate

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

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Synonym(s):
D-Glucose 6-phosphate disodium salt hydrate, G-6-P-Na2, Robison ester
Empirical Formula (Hill Notation):
C6H11Na2O9P · xH2O
CAS Number:
Molecular Weight:
304.10 (anhydrous basis)
Beilstein/REAXYS Number:
5199009
MDL number:
PubChem Substance ID:

form

solid

mol wt

(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)

packaging

pkg of 5 g

manufacturer/tradename

Roche

shipped in

ambient

SMILES string

O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1

InChI key

UUWJZXLTPORJKW-WYFATIGWSA-L

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This Item
G7250346764-MG7879
Glucose-6-phosphate mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

10127647001

Glucose-6-phosphate

D-Glucose 6-phosphate sodium salt ≥98% (HPLC)

G7879

D-Glucose 6-phosphate sodium salt

mol wt

(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)

mol wt

-

mol wt

-

mol wt

-

packaging

pkg of 5 g

packaging

-

packaging

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packaging

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manufacturer/tradename

Roche

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

General description

Disodium salt

Application

Substrate for glucose-6-phosphatase.

Biochem/physiol Actions

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.

Components

77% glucose-6-P (enzymatic), 13% sodium, 8% water

Quality

Contaminants: <0.2% glucose (enzymatic)

Formula variant

C6H11O9PNa2

Other Notes

For life science research only. Not for use in diagnostic procedures.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

does not flash

flash_point_c

does not flash


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C Villar-Palasí et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating
THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
I A ROSE et al.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)

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