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About This Item
Empirical Formula (Hill Notation):
C11H14N2O · C4H4O4
CAS Number:
Molecular Weight:
306.31
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to brown
solubility
H2O: 5 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC2=C(NC(C)=C2CCN)C=C1.OC(/C=C\C(O)=O)=O
InChI
1S/C11H14N2O.C4H4O4/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;5-3(6)1-2-4(7)8/h2-3,6,13-14H,4-5,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
KFEAUMZKRNJEDU-BTJKTKAUSA-N
Related Categories
Biochem/physiol Actions
2-Methylserotonin is a 5-HT3 serotonin receptor agonist.
2-Methylserotonin is a selective full agonist at the 5-HT3 receptor.
2-Methylserotonin maleate, a serotonin type 3 (5-HT3) agonist is used as a training drug in drug discrimination studies. Use of 2-methylserotonin in evolving rats shows to reflect the ontogeny of the spinal 5-HT3 receptor system.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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5-HT3 agonist 2-methylserotonin as a training drug in drug discrimination studies
Glennon R A et al.
Pharmacology, Biochemistry, and Behavior, 41(2), 361-364 (1992)
Antinociceptive effects of intrathecally administered 2-methylserotonin in developing rats
Giordano J
Dev. Brain Res., 98(1), 142-144 (1997)
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