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SML2058

Sigma-Aldrich

5,7-Dihydroxytryptamine hydrobromide

≥94% (HPLC)

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Synonym(s):
3-(2-Aminoethyl)-1H-indole-5,7-diol, 5,7-DHT hydrobromide, 5,7-DiHT hydrobromide, 7-Hydroxyserotonin hydrobromide
Empirical Formula (Hill Notation):
C10H12N2O2 · xHBr
CAS Number:
Molecular Weight:
192.21 (free base basis)
MDL number:

assay

≥94% (HPLC)

form

powder

storage condition

desiccated

color

white to dark brown

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NCCC1=CNC2=C(O)C=C(O)C=C21.[H]Br

InChI

1S/C10H12N2O2/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14/h3-5,12-14H,1-2,11H2

InChI key

LXWHQTNFZDTKBH-UHFFFAOYSA-N

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This Item
SML2591A5879162957
SCH-39166 hydrobromide ≥98% (HPLC)

SML2591

SCH-39166 hydrobromide

6-Hydroxydopamine hydrobromide 95%

162957

6-Hydroxydopamine hydrobromide

assay

≥94% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

95%

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

storage condition

desiccated

storage condition

desiccated

storage condition

-

storage condition

-

solubility

H2O: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to yellow

solubility

-

color

white to dark brown

color

white to beige

color

-

color

-

Biochem/physiol Actions

5,7-Dihydroxytryptamine is a neurotoxin that selectively kills serotonergic neurons.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Pharmacological reports : PR, 65(4), 771-786 (2013-10-23)
This review contains background information on the serotonin system, furthermore the suggestion to introduce the term Contemporary Witness Report (CWR) for a novel type of review and, as the main part, an overview over the history of serotonin discovery as
Pavel M Balaban et al.
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We analyzed changes in the activity of individually identifiable neurons involved in the networks underlying feeding and withdrawal behaviors in snails before, during, and after aversive learning in vitro. Responses to food in the "reinforcing" serotonergic neurons involved in withdrawal
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Behavioural brain research, 295, 35-44 (2015-06-16)
Alcoholism afflicts 1 in 13 US adults, and comorbidity with depression is common. Levels of serotonin (5-HT) metabolites in alcoholic or depressed humans and rat strains are lower compared to healthy counterparts. Rats bred for ethanol (EtOH) preference are common

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