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T3251

Sigma-Aldrich

(±)-α-Tocopherol

synthetic, ≥96% (HPLC)

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Synonym(s):
DL-all-rac-α-Tocopherol, Vitamin E
Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
Molecular Weight:
430.71
Beilstein:
94012
EC Number:
MDL number:
eCl@ss:
34058016
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic

Quality Level

Assay

≥96% (HPLC)

form

liquid

technique(s)

HPLC: suitable

color

faint brown to brown
yellow to very dark yellow

solubility

H2O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible

density

0.950 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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This Item
25802447783T1550000
(±)-α-Tocopherol synthetic, ≥96% (HPLC)

Sigma-Aldrich

T3251

(±)-α-Tocopherol

α-Tocopherol ≥95.5%

Sigma-Aldrich

258024

α-Tocopherol

(±)-α-Tocopherol analytical standard

Supelco

47783

(±)-α-Tocopherol

α-Tocopherol European Pharmacopoeia (EP) Reference Standard

T1550000

α-Tocopherol

assay

≥96% (HPLC)

assay

≥95.5%

assay

-

assay

-

form

liquid

form

liquid

form

liquid

form

solid

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

color

faint brown to brown, yellow to very dark yellow

color

faint brown to brown, yellow to very dark yellow

color

-

color

-

solubility

H2O: insoluble, acetone: miscible, chloroform: miscible, ethanol: miscible, vegetable oils: miscible

solubility

-

solubility

-

solubility

-

Application

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Biochem/physiol Actions

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Preparation Note

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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α-Tocopherol European Pharmacopoeia (EP) Reference Standard

T1550000

α-Tocopherol

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Sigma-Aldrich

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USP

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SAFC

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