1297001
USP
Human chorionic gonadotropin
United States Pharmacopeia (USP) Reference Standard
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Chorionic gonadotropin human, Choriogonin, HCG
Recommended Products
grade
pharmaceutical primary standard
API family
gonadotropin
mol wt
37.9 kDa
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
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General description
Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Application
- Comprehensive Prenatal Screening: Human chorionic gonadotropin (hCG) is crucial in combined first-trimester screening and invasive diagnostics for chromosomal aberrations, offering insights into prenatal health and improving detection rates compared with non-invasive prenatal testing (NIPT). This underscores hCG′s vital role in early gestational health assessments (Gadsbøll et al., 2024).
- Twin Pregnancy Outcomes: hCG levels are studied for their association with adverse outcomes in twin gestations, providing valuable data for managing and monitoring high-risk pregnancies. This research highlights hCG′s predictive value in obstetrics, aiding in the anticipatory management of potential complications (Yamasato and Ono, 2024).
- Missed Abortion Treatment: The effectiveness of Nigella sativa oil, influenced by hCG levels, on the outcomes of missed abortions is explored through a randomized clinical trial. This study demonstrates the potential for integrating hCG monitoring into therapeutic strategies to improve pregnancy outcomes (Mohammadi et al., 2024).
- Germ Cell Testicular Tumor Biomarkers: The role of hCG as a biomarker in germ cell testicular tumors is examined, enhancing the understanding of tumor biology and improving diagnostic accuracy. This research is pivotal for developing targeted therapies and improving prognostic evaluations in oncology (Kılınç et al., 2024).
- Molar Cesarean Scar Ectopic Pregnancy: Studies involving hCG focus on its implications in rare cases of molar cesarean scar ectopic pregnancies, providing insights into unusual gestational complications. This research is crucial for developing guidelines and treatment protocols in exceptionally complex pregnancy cases (Hosseinimousa et al., 2024).
Packaging
1 vial, 530 USP units per package
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
This product is part of the USP Biologics program.
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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