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MilliporeSigma

Bioprocessing Systems

Bioprocessing Single-Use Bioreactors

Our Bioprocessing systems include an extensive range of products to meet your unique manufacturing needs. From single-use to multi-use, upstream to downstream, our portfolio of bioprocessing systems has a solution to support every step of your manufacturing journey.   



Three bioprocessing Mobius® single-use bioreactors. Mobius® Breez Microbioreactor on left, Mobius® 3 L Single-Use Bioreactor in center, and Mobius® iFlex Bioreactors on right.

Bioprocessing Single-Use Bioreactors

Mobius® single-use bioreactors are scalable, configurable, and reliable, able to perform fed-batch and perfusion bioprocessing at any scale from benchtop to full-scale production.

Single-Use Mixers

Our complete range of Mobius® single-use mixing solutions can meet your needs for mixing pharmaceutical ingredients from intermediate to final drug products, as well as preparation of process solutions such as buffers and media.

Single-Use Mixers

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Tangential Flow Filtration Holders & Systems
Tangential Flow Filtration Holders & Systems

Our tangential flow (crossflow) filtration systems are engineered for low hold-up volume, maximum volume concentration, and optimal product recovery in single-use and multi-use applications from process development to large-scale manufacturing, with compatible holders available for expendables.

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Chromatography Systems for Bioprocessing
Chromatography Systems

We provide standard and custom systems from pilot to process-scale, offering robust and consistent performance with the processing flexibility you need. 

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Integrity Testers
Integrity Testers

With many biopharmaceutical manufacturers now testing filters before and after use, there is a need for non-destructive test methods that are fast, reliable, and repeatable. The Integritest® 5 automated test instrument meets this need by enabling non-destructive integrity testing , with the flexibility to add a paired Exact-Air™ II water-based test unit for hydrophobic filters.

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Clarification Filter Holders & Systems
Clarification Filter Holders & Systems

Flexible, easy-to-use filter holders are a key component of the Pod system’s modular design, enabling scalable filtration that meets your manufacturing demands without increasing footprint.

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Chromatography Columns for Bioprocessing
Chromatography Columns for Bioprocessing

Chromatography columns are critical to the successful separation of your valuable molecules. We provide columns from lab scale to pilot and process scale.

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Virus Filter Holders and Systems
Virus Filter Holders and Systems

We offer a wide range of flexible, easy-to-use filter holders and systems that provide the highest levels of retention assurance and processing efficiency across a broad range of feed streams, enabling scalable virus filtration that meets your manufacturing demands.

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Stainless Steel Connectors, Valves & Mixers for Bioprocessing
Stainless Steel Connectors, Valves & Mixers for Bioprocessing

NovAseptic® hardware, a range of high-performing risk-free fluid handling components, exceeds the requirements for clean, sanitary processes. With our wide range of mixers, valves, and connectors, you can easily improve the safety, quality, potency, and purity of your product while minimizing processing time.

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