Skip to Content
MilliporeSigma
  • Magnetic mesoporous silica nanoparticles for potential delivery of chemotherapeutic drugs and hyperthermia.

Magnetic mesoporous silica nanoparticles for potential delivery of chemotherapeutic drugs and hyperthermia.

Dalton transactions (Cambridge, England : 2003) (2014-09-06)
Cuilian Tao, Yufang Zhu
ABSTRACT

Magnetic mesoporous silica (MMS) nanoparticles with controllable magnetization have been synthesized by encapsulating Fe3O4 nanoparticles in a mesoporous silica matrix. The structure, magnetic heating capacity and drug delivery ability of MMS nanoparticles were evaluated. The results showed that MMS nanoparticles had an average particle size of 150 nm and showed low cytotoxicity and efficient cell uptake ability. MMS nanoparticles exhibited a sustained drug release in the medium of pH 5.0, but a very slow release in the medium of pH 7.4. On the other hand, MMS nanoparticles could controllably generate heat to reach the hyperthermia temperature within a short time upon exposure to an alternating magnetic field due to the superparamagnetic behavior and controllable magnetization. Therefore, MMS nanoparticles could provide a promising multifunctional platform for the combination of chemotherapy and hyperthermia for cancer therapy.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Iron(III) chloride, sublimed grade, ≥99.9% trace metals basis
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
USP
Dehydrated Alcohol, United States Pharmacopeia (USP) Reference Standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Doxorubicin hydrochloride, 98.0-102.0% (HPLC)
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Doxorubicin hydrochloride, suitable for fluorescence, 98.0-102.0% (HPLC)
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Iron(III) chloride, anhydrous, powder, ≥99.99% trace metals basis
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Trolamine, European Pharmacopoeia (EP) Reference Standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
USP
Doxorubicin hydrochloride, United States Pharmacopeia (USP) Reference Standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Doxorubicin hydrochloride, European Pharmacopoeia (EP) Reference Standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, pellets, semiconductor grade, 99.99% trace metals basis
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, flakes
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, powder
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, beads, 16-60 mesh, reagent grade, 97%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Ethanol Fixative 80% v/v, suitable for fixing solution (blood films)
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 1.0 N, BioReagent, suitable for cell culture
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
3-Ethyl-2,4-pentanedione, mixture of tautomers, 98%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Supelco
Sodium hydroxide solution, 49-51% in water, eluent for IC
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 0.2 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 0.05 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Supelco
Sodium hydroxide concentrate, 0.1 M NaOH in water (0.1N), Eluent concentrate for IC
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 7 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, BioUltra, for luminescence, ≥98.0% (T), pellets
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 0.1 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 1 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Ethanol, JIS first grade, 94.8-95.8%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 0.01 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Ethanol, JIS special grade, 94.8-95.8%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Supelco
Ethanol solution, certified reference material, 2000 μg/mL in methanol
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, BioUltra, for molecular biology, 10 M in H2O
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide solution, 4 M
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00
Sigma-Aldrich
Sodium hydroxide, JIS special grade, ≥96.0%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on March 23, 2025
$135.00