561037

3,4-ジフルオロフェニルマグネシウムブロミド 溶液

0.5 M in THF

• 化学式: F₂C₆H₃MgBr
• CAS番号: 90897-92-0
• 分子量: 217.29
• MDL番号: MFCD00672004
• UNSPSCコード: 12352103
• PubChem Substance ID: 24879910
• NACRES: NA.22

特性

• 反応適合性: reaction type: Grignard Reaction
• 品質水準: 100
• 濃度: 0.5 M in THF
• bp: 65 °C
• 密度: 0.965 g/mL at 25 °C
• 官能基: fluoro
• 保管温度: 2-8°C
• SMILES記法: Fc1ccc([Mg]Br)cc1F
• InChI: 1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1
• InChI Key: WZHAVYGMKGPNFN-UHFFFAOYSA-M

詳細

アプリケーション

3,4-Difluorophenylmagnesium bromide can be used:

• To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
• In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
• In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
• In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

法的情報

Rieke^® Metals, Inc.の製品です。

安全性情報

• ピクトグラム: GHS02,GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H302,H319,H335,H351
• 注意書き: P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• 危険有害性の分類: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 補足的ハザード: EUH019
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 1.0 °F - closed cup
• 引火点(℃): -17.2 °C - closed cup