764787

ポリ(ラクチド-コ-グリコリド)-ブロック-ポリ(エチレングリコール)-ブロック-ポリ(ラクチド-コ-グリコリド)

average M_n (1,000-1,000-1,000), lactide:glycolide 50:50

• 別名: PLGA-PEG-PLGA
• UNSPSCコード: 12162002
• NACRES: NA.23

特性

• 詳細: typical PEG PDI<1.1; overall PDI<1.2 (THF, PEO)
• 形状: liquid
• 原料比: lactide:glycolide 50:50
• 分子量: PEG average M_n 1,000; PLGA average M_n 2000; average M_n (1,000-1,000-1,000)
• 劣化の時間枠: 1-2 weeks
• PDI: <1.2
• 保管温度: 2-8°C

詳細

詳細

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

アプリケーション

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

特徴および利点

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable