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アッセイ
>99% (TLC)
フォーム
powder
包装
pkg of 1 × 5 mg (791300P-5mg)
メーカー／製品名
Avanti Research™ - A Croda Brand 791300P
輸送温度
dry ice
保管温度
−20°C
関連するカテゴリー
詳細
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) comprises synthetic phospholipid derivative of ethanolamine.
This chelate is used for preparing MRI contrast agents.
アプリケーション
18:0 PE-DTPA (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (ammonium salt)) has been used to chelate liposome-based cationic adjuvant formulation (CAF01). It has also been used in the liposome preparation for imaging studies
生物化学的／生理学的作用
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (18:0 PE-DTPA) or PE-DTPA binding and interaction with the Toll-like receptor-2 regulates immune response . PE-DTPA acts as a lipopolysaccharide antagonist and elicits rescue functionality in sepsis by blocking nuclear factor κ -light-chain-enhancer of activated B cells based transcription.
包装
5 mL Amber Glass Screw Cap Vial (791300P-5mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
791300P-VAR:
791300P-BULK:
791300P-5MG:
最新バージョンのいずれかを選択してください：
Brian Mog et al.
Nanotheranostics, 3(4), 342-355 (2019-11-15)
Specific targeting of inflammation remains a challenge in many pathologies, because of the necessary balance between host tolerance and efficacious inflammation resolution. Here, we discovered a short, 4-mer peptide which possesses antagonist properties towards CC chemokine receptor 2 (CCR2), but
Chunghyun Lee et al.
Molecules and cells, 27(2), 251-255 (2009-03-12)
Sepsis is the leading cause of death in critically ill patients. Today, around 60% of all cases of sepsis are caused by Gram-negative bacteria. The cell wall component lipopoly-saccharide (LPS) is the main initiator of the cascade of cellular reactions
Aneesh Thakur et al.
Frontiers in immunology, 9, 2825-2825 (2018-12-18)
Pulmonary tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), remains a global pandemic, despite the widespread use of the parenteral live attenuated Bacillus Calmette-Guérin (BCG) vaccine during the past decades. Mucosal administration of next generation TB vaccines has great
Zahraa S Al-Ahmady et al.
ACS nano, 13(11), 12470-12486 (2019-11-07)
The development of effective therapies for stroke continues to face repeated translational failures. Brain endothelial cells form paracellular and transcellular barriers to many blood-borne therapies, and the development of efficient delivery strategies is highly warranted. Here, in a mouse model
Jin Young Kang et al.
Immunity, 31(6), 873-884 (2009-11-26)
Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand specificity is controlled by whether it heterodimerizes with TLR1 or TLR6. We have determined the crystal structures of TLR2-TLR6-diacylated lipopeptide, TLR2-lipoteichoic acid, and TLR2-PE-DTPA
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