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Merck

LM1102

Avanti

17:0-20:4 PE

Avanti Research - A Croda Brand LM1102, methanol solution

別名:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine

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About This Item

実験式(ヒル表記法):
C42H76NO8P
CAS番号:
分子量:
754.03
UNSPSCコード:
12352211
NACRES:
NA.25

フォーム

methanol solution

包装

pkg of 1 × 1 mL (LM1102-1EA)

メーカー/製品名

Avanti Research - A Croda Brand LM1102

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

輸送温度

dry ice

保管温度

−20°C

SMILES記法

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O

InChI

1S/C42H76NO8P/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43)38-48-41(44)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2/h11,13,17,19,21,23,27,29,40H,3-10,12,14-16,18,20,22,24-26,28,30-39,43H2,1-2H3,(H,46,47)/b13-1

アプリケーション

17:0-20:4 PE or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine has been used as an internal standard:
  • for phospholipid extraction from mitochondria for quantitative mass spectrometry (MS) analysis
  • for lipid analysis of murine brain lipid extract using Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS)
  • for lipid quantification using liquid chromatography- mass spectrometry (LC-MS)
  • in the preparation of total lipid extracts by LC-MS
  • for ratiometric quantification of phosphoethanolamine (PE) using LC-MS

生物化学的/生理学的作用

Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane. It is associated with the phospholipid turnover. PE is also found to prevent tumor progression.

包装

2 mL Amber Glass Sealed Ampule (LM1102-1EA)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

ピクトグラム

FlameSkull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

ターゲットの組織

Eyes

保管分類コード

3 - Flammable liquids

WGK

WGK 2

引火点(°F)

49.5 °F - closed cup

引火点(℃)

9.7 °C - closed cup


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試験成績書(COA)

Lot/Batch Number

申し訳ございませんが、現在この製品のCOAをオンラインで入手できません。

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Di Ding et al.
Molecular neurobiology, 56(4), 2618-2639 (2018-07-28)
Neurons from the adult central nervous system (CNS) demonstrate limited mRNA transport and localized protein synthesis versus developing neurons, correlating with lower regenerative capacity. We found that deimination (posttranslational conversion of protein-bound arginine into citrulline) undergoes upregulation during early neuronal
Kallol Gupta et al.
Nature protocols, 13(5), 1106-1120 (2018-04-28)
With the recent success in determining membrane protein structures, further detailed understanding of the identity and function of the bound lipidome is essential. Using an approach that combines high-energy native mass spectrometry (HE-nMS) and solution-phase lipid profiling, this protocol can
Andreas Ullen et al.
Free radical biology & medicine, 49(11), 1655-1665 (2010-09-03)
Plasmalogens, 1-O-alk-1'-enyl-2-acyl-sn-glycerophospholipids, are significant constituents of cellular membranes and are essential for normal brain development. Plasmalogens, which contain a vinyl ether bond at the sn-1 position, are preferential targets for hypochlorous acid (HOCl), generated by myeloperoxidase (MPO) from H(2)O(2) and
Laura Montani et al.
The Journal of cell biology, 217(4), 1353-1368 (2018-02-13)
Myelination calls for a remarkable surge in cell metabolism to facilitate lipid and membrane production. Endogenous fatty acid (FA) synthesis represents a potentially critical process in myelinating glia. Using genetically modified mice, we show that Schwann cell (SC) intrinsic activity
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we

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