N-902

ノルトリプチリン-D₃ 塩酸塩 溶液

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₉D₃H₁₈N · HCl
• CAS番号: 136765-48-5
• 分子量: 302.86
• MDL番号: MFCD00198172
• UNSPSCコード: 41116107
• PubChem Substance ID: 329818692
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• フォーム: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 100 μg/mL in methanol (as free base)
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: clinical testing
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: [2H]C([2H])([2H])NCCC=C1C2=C(C=CC=C2)CCC3=C1C=CC=C3.[H]Cl
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H/i1D3;
• InChI Key: SHAYBENGXDALFF-NIIDSAIPSA-N

詳細

詳細

Nortriptyline is a second generation tricyclic antidepressant (TCA) marketed under trade names such as Sensoval, Aventyl^®, and Pamelor^® for treatment of major depression. Nortriptyline is also an active metabolite of the TCA amitriptyline. This certified Snap-N-Spike^® Solution is suitable as an internal standard for quantitation of nortriptyline levels by LC/MS or GC/MS in clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, or medication monitoring applications.

アプリケーション

• Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).: This study demonstrates a robust method for the quantification of tricyclic antidepressants, including Nortriptyline-D3, using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. The approach offers precise measurement essential for pharmacokinetic and neuropharmacological research, aligning with the interests of researchers in pharma and biotech focused on antidepressant metabolism studies (Clarke et al., 2016).

法的情報

Aventyl is a registered trademark of Eli Lilly and Co.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pamelor is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup