コンテンツへスキップ
Merck

S-025

Supelco

JWH-018

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

ログイン組織・契約価格を表示する


About This Item

実験式(ヒル表記法):
C24H23NO
CAS番号:
分子量:
341.45
EC Number:
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material

品質水準

形状

liquid

特徴

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

メーカー/製品名

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

濃度

100 μg/mL in methanol

テクニック

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

アプリケーション

forensics and toxicology
forensics and toxicology

フォーマット

single component solution

保管温度

−20°C

InChI

1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3

InChI Key

JDNLPKCAXICMBW-UHFFFAOYSA-N

詳細

JWH-018 is a synthetic cannabinoid found in several versions of the herbal mixture “Spice.” Illicit use of this Spice cannabinoid centers on its psychoactive effects which mimic those of Δ9-THC in cannabis. While considerably more potent than similar amounts of cannabis, JWH-018 also presents significant challenges for detection by typical Δ9-THC testing assays.
In July, 2009, the US Drug Enforcement Agency (DEA) listed JWH-018 on its Drugs and Chemicals of Concern list. In addition to reported seizures of Spice in Ohio and Florida, several states have passed legislative action restricting the sale or possession of JWH-018 including Alabama, Arkansas, Georgia, Kansas, Kentucky, North Dakota, and Tennessee.

アプリケーション


  • Investigating Synthetic Cannabinoids in Leukemia: A study exploring the effects of synthetic cannabinoids like JWH-018 on leukemia and leukemic stem cells offers insights into potential therapeutic applications. This research highlights the value of JWH-018 as a tool for understanding cancer pathogenesis and developing new treatments, reinforcing its significance in biomedical research (Salcin et al., 2024).

    • Yeast Biosensor for Cannabinoid Detection: Research on a GPCR-based yeast biosensor for point-of-use cannabinoid determination, including synthetic cannabinoids such as JWH-018, showcases innovative biotechnological applications. This study demonstrates the biosensor′s utility in biomedical and environmental monitoring, potentially influencing drug safety and public health strategies (Miettinen et al., 2022).

    • Molecular Signaling of Synthetic Cannabinoids: A comparative study on the molecular signaling of synthetic cannabinoids, including JWH-018, provides critical data on their effects on CB1 and CB2 receptors. This research is pivotal for pharmacological studies aiming to understand the complex interactions of these compounds at the molecular level, thereby aiding in the development of targeted therapies for various conditions (Andersen et al., 2021).

    • Enhancing Drug Analysis Sensitivity: A study aimed at enhancing the nonfouling properties and sensitivity of Surface-Enhanced Raman Scattering (SERS) substrates for potent drug analysis, including JWH-018, highlights its application in forensic science. This research contributes to more accurate and rapid detection methods, essential for effective law enforcement and therapeutic monitoring (Masterson et al., 2021).




法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

ピクトグラム

FlameSkull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

ターゲットの組織

Eyes

保管分類コード

3 - Flammable liquids

WGK

WGK 2

引火点(°F)

49.5 °F - closed cup

引火点(℃)

9.7 °C - closed cup


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

消防法

第4類:引火性液体
アルコール類
危険等級II

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

S-025-1ML:
S-025-CC:
S-025-CHK:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

資料

This study demonstrates the impact of various mobile phase modifiers on the separation; formate modifiers outperform acetate in terms of MS signals (or sensitivity) and chromatographic resolution.

A large variety of cannabinoid drug standards, along with an HPLC method with the Supelco Ascentis® Express RP-Amide column, are presented in this article.

Chromatograms

application for HPLCapplication for HPLCapplication for HPLC

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)