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安全性情報

AB2253

Sigma-Aldrich

Anti-Doublecortin Antibody

serum, from guinea pig

別名:

Anti-Doublecortin Antibody, AB2253 | Sigma-Aldrich

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

guinea pig

品質水準

抗体製品の状態

serum

抗体製品タイプ

primary antibodies

クローン

polyclonal

化学種の反応性

rat, mouse

化学種の反応性(ホモロジーによる予測)

human (based on 100% sequence homology)

テクニック

immunofluorescence: suitable (Frozen tissue sections)
immunohistochemistry: suitable (Paraffin)
western blot: suitable

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... DCDC1(341019)

詳細

Anti-Doublecortin, Cat. No. AB2253, is a guinea pig polyclonal antibody that detects Doublecortin and is tested for use in Immunohistochemistry (Paraffin) and Immunofluorescence, and Western Blotting.
Target molecular weight ~42 kDa observed;40.61 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

特異性

Reactivity with other species has not been determined.
This Guinea pig polyclonal antibody detects doublecortin in murine and rat species. It targets an epitope with in 17 amino acids from the C-terminal region.

免疫原

Epitope: C-Terminus
Recombinant Peptide.

アプリケーション

Anti-Doublecortin Antibody has been used in immunohistochemistry and immunofluorescence staining.

生物化学的/生理学的作用

Doublecortin (DCX) is identified as an important marker for neurogenesis. It serves as a valuable tool for studying and comparing the process of neurogenesis across different species.

品質

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Doublecortin in rat brain tissue lysate.

ターゲットの説明

~45 kDa observed; 40.57 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

関連事項

Replaces: AB5910

物理的形状

GST Depletion
GST-Depleted Guinea Pig Sera with 0.05% Sodium Azide

保管および安定性

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

アナリシスノート

Control
Rat Brain lysate.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

AB2253:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Jacques Balthazart et al.
Brain, behavior and evolution, 84(1), 1-4 (2014-07-19)
Commentary on “Evaluating the Predictive Value of Doublecortin as a Marker for Adult Neurogenesis in Canaries (Serinus canaria)” by Michiel Vellema, Moritz Hertel, Susan L. Urbanus, Annemie Van der Linden, and Manfred Gahr (Journal of Comparative Neurology 2014, 522 :
Embryonic Nkx2. 1-expressing neural precursor cells contribute to the regional heterogeneity of adult V-SVZ neural stem cells
Delgado RN and Lim DA
Developmental Biology, 407(2), 265-274 (2015)
Tomás P Bachor et al.
Neurobiology of disease, 108, 13-28 (2017-07-27)
Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairment and dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularly vulnerable. Therefore, we evaluated the different components of the mouse subventricular
Tania Campos-Ordoñez et al.
Experimental neurology, 261, 236-244 (2014-05-27)
Hydrocephalus can develop secondarily to a disturbance in production, flow and/or absorption of cerebrospinal fluid. Experimental models of hydrocephalus, especially subacute and chronic hydrocephalus, are few and limited, and the effects of hydrocephalus on the subventricular zone are unclear. The
Combination treatment with ethyl pyruvate and IGF-I exerts neuroprotective effects against brain injury in a rat model of neonatal hypoxic-ischemic encephalopathy
Rong Z, et al.
International Journal of Molecular Medicine, 36(1), 195-203 (2015)

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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