おすすめの製品
品質水準
アッセイ
≥95% (HPLC)
テクニック
HPLC: suitable
gas chromatography (GC): suitable
色
white
抗生物質活性スペクトル
Gram-negative bacteria
Gram-positive bacteria
フォーマット
neat
作用機序
cell wall synthesis | interferes
enzyme | inhibits
保管温度
2-8°C
SMILES記法
S1C(NC(C1(C)C)C(=O)O)C(NC(=O)Cc2ccccc2)C(=O)O
InChI
1S/C16H20N2O5S/c1-16(2)12(15(22)23)18-13(24-16)11(14(20)21)17-10(19)8-9-6-4-3-5-7-9/h3-7,11-13,18H,8H2,1-2H3,(H,17,19)(H,20,21)(H,22,23)
InChI Key
HCYWNSXLUZRKJX-UHFFFAOYSA-N
詳細
This product is a penicilloic acid with the N-acyl group phenylacetyl as side-chain. In alkaline medium, 5R,6R-Benzylpenicilloic acid epimerizes slowly to 5S,6R-benzylpenicilloic acid until equilibrium.
アプリケーション
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
その他情報
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください:
ACS chemical biology, 8(10), 2112-2116 (2013-08-01)
β-Lactam antibiotics react with penicillin binding proteins (PBPs) to form relatively stable acyl-enzyme complexes. We describe structures derived from the reaction of piperacillin with PBP3 (Pseudomonas aeruginosa) including not only the anticipated acyl-enzyme complex but also an unprecedented complex with
Degradation of benzylpenicillin at pH 7.5 to D-benzylpenicilloic acid.
Nature, 187, 939-940 (1960-09-10)
Journal of pharmaceutical sciences, 73(1), 125-128 (1984-01-01)
5R,6R-Benzylpenicilloic acid was found to epimerize slowly in alkaline media to 5S,6R-benzylpenicilloic acid until equilibrium was established. Epimerization proceeded via the imine tautomer of penamaldic acid rather than the enamine form and was found to favor the 5S,6R-epimer at equilibrium.
Journal of chromatography. A, 1187(1-2), 103-110 (2008-02-26)
A rapid, sensitive and selective ion-pair reversed-phase liquid chromatography-electrospray ionization isotope dilution tandem mass spectrometry (IP-LC-ESI-ID-MS/MS) was developed for quantitative analysis of free intracellular metabolites in cell cultures. As an application a group of compounds involved in penicillin biosynthesis pathway
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(7-8), 533-540 (2011-02-09)
A rapid, sensitive, and specific method for the determination of amoxicillin (AMO), amoxicilloic acid (AMA), amoxicillin diketopiperazine-2',5'-dione (DIKETO), penicillin G (PEN G), benzylpenicilloic acid (BPA-1), benzylpenilloic acid (BPA-2), and benzylpenillic acid (BPA-3) in bovine milk using ultra-high-performance liquid chromatography-tandem mass
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