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Merck

D0730000

D-パンテノール

European Pharmacopoeia (EP) Reference Standard

別名:

(R)-(+)-2,4-ジヒドロキシ-N-(3-ヒドロキシプロピル)-3,3-ジメチルブチラミド, (R)-2,4-ジヒドロキシ-3,3-ジメチルブチリック 3-ヒドロキシプロピルアミド, D-パンテニルアルコール, デクスパンテノール, プロビタミンB

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About This Item

実験式(ヒル表記法):
C9H19NO4
CAS番号:
分子量:
205.25
Beilstein:
1724947
MDL番号:
UNSPSCコード:
41116107
PubChem Substance ID:
NACRES:
NA.24

由来生物

synthetic

グレード

pharmaceutical primary standard

認証

EP Reference Standard

APIファミリー

dexpanthenol

フォーム

solid

メーカー/製品名

EDQM

テクニック

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

密度

1.20 g/mL at 20 °C (lit.)

アプリケーション

pharmaceutical (small molecule)

フォーマット

neat

保管温度

2-8°C

SMILES記法

CC(C)(CO)[C@@H](O)C(=O)NCCCO

InChI

1S/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m0/s1

InChI Key

SNPLKNRPJHDVJA-ZETCQYMHSA-N

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詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Dexpanthenol, an alcoholic analog of pantothenic acid, can be potentially applied for skin wound healing application. It is utilized in multi-vitamin formulations, as a parenteral drug and certain cosmetic preparations. When absorbed by the skin, it is transformed into pantothenic acid (vitamin B5), which has implications in the biosynthesis of coenzyme A.

アプリケーション

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

その他情報

Sales restrictions may apply.

保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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Dexpanthenol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 2016(3), 2227-2228 (2017)
Simultaneous determination of mepyramine maleate, lidocaine hydrochloride, and dexpanthenol in pharmaceutical preparations by partial least-squares multivariate calibration
Aksu O, et al.
Analytical Letters, 39(4), 751-761 (2006)
Simultaneous quantification of dexpanthenol and resorcinol from hair care formulation using liquid chromatography: method development and validation
De, Amit Kumar and Chowdhury, Partha Pratim and Chattapadhyay, Shyamaprasad
Scientifica, 2016(3), 983-988 (2016)
Anti-inflammatory and anti-oxidative effects of dexpanthenol on lipopolysaccharide induced acute lung injury in mice
Li-Mei W, et al.
Inflammation, 39(5), 1757-1763 (2016)
Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations.
Kulikov U A and Zinchenko A A.
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 983-988 (2007)

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