おすすめの製品
グレード
analytical standard
品質水準
テクニック
HPLC: suitable
gas chromatography (GC): suitable
アプリケーション
forensics and toxicology
pharmaceutical (small molecule)
veterinary
フォーマット
neat
SMILES記法
CN1C(C(=O)Nc2cc(C)on2)=C(O)c3ccccc3S1(=O)=O
InChI
1S/C14H13N3O5S/c1-8-7-11(16-22-8)15-14(19)12-13(18)9-5-3-4-6-10(9)23(20,21)17(12)2/h3-7,18H,1-2H3,(H,15,16,19)
InChI Key
YYUAYBYLJSNDCX-UHFFFAOYSA-N
遺伝子情報
human ... PTGS1(5742) , PTGS2(5743)
詳細
Isoxicam is a long acting anti-inflammatory agent belonging to the oxicam group, and helps in relieving the symptoms of degenerative joint disease and rheumatoid arthritis. Its mode of action involves the ability to inhibit prostaglandin synthesis by suppressing the formation of cyclooxygenase and subsequent prostaglandin.
アプリケーション
Isoxicam may be used as an internal standard for the quantification of meloxicam in pharmaceutical preparations and as an analytical reference standard for the quantification of the analyte in biological samples using different analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
保管分類コード
11 - Combustible Solids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
I1762-BULK:
I1762-5G:
I1762-1G:
I1762-VAR:
I1762-10G:
最新バージョンのいずれかを選択してください：
J Sassard et al.
Prostaglandins, leukotrienes, and essential fatty acids, 38(2), 107-111 (1989-11-01)
The effects of a 7 day-treatment with isoxicam (200 mg/24 h) on the urinary excretion of prostaglandins (PG) were compared to those of indomethacin (150 mg/24 h) in a double-blind randomized study conducted in 18 patients with degenerative arthritic disease
W Kullich et al.
Zeitschrift fur Rheumatologie, 49(2), 77-81 (1990-03-01)
The influence of the oxicams, a special group of non-steroidal anti-inflammatory drugs, to the sister chromatid exchange (SCE) was determined on human lymphocytes in vitro and in vivo. The analysis of SCE is a sensitive parameter indicating chromosomal damage. The
H Fenner
Scandinavian journal of rheumatology. Supplement, 65, 97-101 (1987-01-01)
The chronicity of the inflammatory process requires persistent tissue concentrations of non-steroidal anti-inflammatory drugs (NSAIDs), best achieved by using a drug with a long half-life as a once-daily regimen. The oxicams proved to be one of the most promising classes
H Fenner
European journal of rheumatology and inflammation, 9(2), 3-7 (1987-01-01)
The chronicity of the inflammatory process requires persistent tissue concentrations of non-steroidal anti-inflammatory drugs (NSAIDs), best achieved by using a drug with a long half-life as a once-daily regimen. The oxicams proved to be one of the most promising classes
F Bree et al.
Biochemical pharmacology, 38(5), 753-758 (1989-03-01)
Isoxicam binding to HSA was studied using equilibrium dialysis and fluorescence methods. It was shown that this drug binds to or near site I (warfarin or azapropazone site) and to site II (the diazepam site) as a secondary site, although
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