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グレード
certified reference material
pharmaceutical secondary standard
品質水準
認証
traceable to Ph. Eur. P3350000
traceable to USP 1568506
APIファミリー
proline
CofA
current certificate can be downloaded
テクニック
HPLC: suitable
gas chromatography (GC): suitable
mp
228 °C (dec.) (lit.)
アプリケーション
pharmaceutical (small molecule)
フォーマット
neat
保管温度
2-30°C
SMILES記法
OC(=O)[C@@H]1CCCN1
InChI
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChI Key
ONIBWKKTOPOVIA-BYPYZUCNSA-N
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詳細
L-Proline is a non-essential amino acid. Peptides bond to proline, making it a useful building block for proteins. It can be used as a cell culture media component for the commercial biomanufacturing of therapeutic recombinant proteins and monoclonal antibodies.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
アプリケーション
L-Proline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
アナリシスノート
このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。
その他情報
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
脚注
To see an example of a Certificate of Analysis for this material enter LRAC3756 in the slot below. This is an example certificate only and may not be the lot that you receive.
おすすめ製品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
保管分類コード
13 - Non Combustible Solids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
PHR1332-500MG:
PHR1332-500MG-PW:
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Proline
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 3683-3683 (2018)
Daniel R Knight et al.
Applied and environmental microbiology, 81(1), 119-123 (2014-10-19)
Clostridium difficile is an important enteric pathogen of humans and the cause of diarrhea and enteritis in neonatal pigs. Outside Australia, prevalence in piglets can be up to 73%, with a single PCR ribotype (RT), 078, predominating. We investigated the
Marco Scocchi et al.
Cellular and molecular life sciences : CMLS, 68(13), 2317-2330 (2011-05-20)
Proline-rich antimicrobial peptides are a group of cationic host defense peptides of vertebrates and invertebrates characterized by a high content of proline residues, often associated with arginine residues in repeated motifs. Those isolated from some mammalian and insect species, although
Frederic Bringaud et al.
Frontiers in bioscience (Landmark edition), 17, 349-374 (2011-12-29)
Trypanosomatids are a large family of unicellular eukaryotes, many of which are parasites in higher eukaryotes including man. Much of our understanding of metabolism in these organisms has been gained form the study of the human infective representatives (Trypanosoma brucei
John M Curto et al.
Organic letters, 16(7), 1948-1951 (2014-03-29)
The first asymmetric synthesis of α-allyl-α-aryl α-amino acids by means of a three-component coupling of α-iminoesters, Grignard reagents, and cinnamyl acetate is reported. Notably, the enolate from the tandem process provides a much higher level of reactivity and selectivity than
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